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Leukocyte Adhesion Defect Panel

Important Note

Note: limited specimen stability - see Sample Requirements below - do NOT refrigerate.

Children's Outpatient Blood Draw areas and Community Services - order "T&B Community Service" (specific tests will be ordered in Cell Markers Lab) and submit copy of requisition with specimen.

For more information call Cell Markers (206) 987-2560.

Additional Codes

MULTIPLE PANEL SELECTIONS:

Ordering Providers: select desired tests on requisition or in CIS - see table below. 

 

Clinical System Name Panel Information Lab Orderable
Leukocyte Adhesion Defect Full Panel LAD - CD11a, CD11b, CD11c, CD18 CD18/CD11abc
Leukocyte Adhesion Study CD18 Only LAD - CD18 Only CD18 Only

Panels can be ordered alone, or in combination with other T and B Panels - duplicate tests will not be charged.

Clinical System Name

Multiple selections - see chart above

Synonyms

CD18 Only
CD18/CD11abc
LAD CD18 Only
LAD Full Panel CD18, CD11abc
Leukocyte Adhesion Defect Full Panel
Leukocyte Adhesion Study CD18 Only

Description

The leukocyte adhesion panel is used to evaluate for the presence or absence of key molecules on white blood cells that are necessary for their migration out of peripheral blood circulation and into the tissues.

Sample Requirements

Specimen:  Whole Blood

Container(s):  Lavender/EDTA; Dk Green/Heparin also acceptable from referring labs if CBC & differential results submitted

Preferred Vol:  2-3 mL

Minimum Vol:  2 mL; no microtainers

 

Note:  Specimens received after 1430 will be held and testing will be performed the next working day. 

 

 

  Collected in-house at Seattle Children's Collected off-site (including SCH Bellevue)
M-Th collect any time collect any time
Friday collect any time ok if received at SCH main lab same day, if not do not collect
Saturday ok if collected before 12 noon do not collect
day before a holiday ok if collected before 12 noon must be received at SCH main lab before 12 noon
Sunday ok if collected after 12 noon (to be tested next morning)

ok if collected after 12 noon (to be tested next morning)

Sunday before a holiday Monday do not collect do not collect
Holiday ok if collected after 12 noon (to be tested next morning) ok if collected after 12 noon (to be tested next morning)

 

Children's Outpatient Blood Draw areas and Community Services - order "T&B Community Services" (specific tests will be ordered in Cell Markers Lab) and submit copy of requisition with specimen.

Processing Instructions

Reject due to:  clotted specimen, Microtainers, Refrigerated

Spin: N

Aliquot: N

Temp:  RT - DO NOT REFRIGERATE

Note:  Have Core Lab run specimen through hematology analyzer and send a copy of the results and community service requisition (if applicable) with specimen to Cell Markers.

Storage location: Days:  Transport specimen, copy of community service requisition (if applicable), and labels to 10th floor Cell Markers (station #280).    Eves/Nights:  Store specimen, copy of community service requisition (as applicable), and labels in the Cell Markers RT box in CPA.

 

Off-site collection:  Keep whole blood at room temperature. Referring labs may send CBC w/differential results from the same collection along with the sample.  Transport specimens to Seattle Children's Hospital address on requisition: Laboratory OC.8.720, 4800 Sand Point Way NE, Seattle, WA  98105. 

Stability

Temperature Time
Room temp EDTA - 30 hours; Heparin - 48 hours
Refrigerated N
Frozen N

 

Availability

STAT Performed TAT
N M-F, Sa (0730-1200) 2-3 days

Note: limited specimen stability - see Sample Requirements

Performing Laboratory

Seattle Children's Laboratory    

Department

Department:  Cell Markers

Phone Number: 206-987-2560

 

Reference Range

Reference values accompany patient report.
 

Methodology

Method:  Flow Cytometry

Analytical Volume:  dependent on patient's white count and testing requested

Limitations:

CPT Codes

 

Name Panel Information CPT CODE(S)
Leukocyte Adhesion Defect Full Panel LAD - CD11a, CD11b, CD11c, CD18  
     CM AB IF CD18 1st   86356
     CM AB IF CD11A   86356
     CM AB IF CD11B   86356
     CM AB IF CD11C   86356
     
Leukocyte Adhesion Study CD18 Only LAD - CD18 Only 86356