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T3 Uptake

Important Note

T3 Uptake is no longer offered at Seattle Children's unless ordered by a Seattle Children's Endocrinologist.  Our Laboratory Test Utilization Management Team has determined that there is limited proven, evidence-based clinical utility for this test for evaluation of thyroid dysfunction or other clinical indications.

Additional Codes

T Uptake

Sample Requirements

Phlebotomists: Do not collect blood for T3 Uptake, unless ordered by a Seattle Children's Endocrinologist.

Notify ordering provider that this test is no longer available at Seattle Children's and we do not send this test out to other reference laboratories. Our Laboratory Test Utilization Management Team has determined that there is limited proven, evidence-based clinical utility for this test for thyroid dysfunction or other clinical indications.

 

IIf a provider wishes to discuss T3 Uptake testing further, a Laboratory Director may be reached through Lab Client Services at 206-987-2617.

 

For endocrinologist requests:

 

Specimen: Whole Blood

Container: Gold SST, Red

Volume: 0.6 mL

Collection Instructions:

1. Serum gel tubes should be centrifuged within 2 hours of collection.

2. Red-top tubes should be centrifuged and aliquoted within 2 hours of collection.

Clinical Utility

TSH is the single best screening test for thyroid dysfunction, and Free T4 is useful when evaluating hypothyroidism. These tests are performed daily in Seattle Children’s Laboratory.

 

There are several professional societies who have published this recommendation, including  The American Association of Clinical Endocrinologists and the American Thyroid Association. (ATA/AACE Guidelines for Hypothyroidism in Adults, Endocr Pract. 2012; 18 (6)).

 

If a provider wishes to discuss T3 Uptake testing further, a Laboratory Director may be reached through Lab Client Services at 206-987-2617.