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Test Code ANTI DNA DNA Antibody (Double-Stranded)

Clinical System Name

DNA Antibody (Double-stranded)

Synonyms

Anti DNA Antibodies
Anti double stranded DNA
Anti dsDNA
Anti Native DNA
Anti-DS DNA
DNA Binding

Description

This assay is used in the detection and quantitation of autoantibodies to aid in the diagnosis of autoimmune disease, typically in evaluating patients with signs and symptoms consistent with systemic lupus erythematosis (SLE) and in monitoring patients with documented SLE for flares in disease activity.  

Sample Requirements

Specimen:  Whole Blood

Container(s):  Gold SST, Red, Dark Green/Sodium Heparin, Lavendar/EDTA

Preferred Vol:  2 mL

Minimum Vol:  1 mL

Processing Instructions

Reject due to

Spin:  Y

Aliquot:  Y

Temp:  2-8 C

Storage location:  CPA Refrigerator, FrigF Rack. 

 

Off-site collection:  Avoid hemolysis. Spin blood, refrigerate 1 mL serum/plasma in a polypropylene aliquot tube.

Stability

Temperature Time
Room temp  
Refrigerated 7 d
Frozen 6 m

 

Availability

STAT Performed TAT
N* M-F 1-3 d

 

*Available STAT only upon approval of Seattle Children's Hospital Pathologist on call.

Performing Laboratory

Seattle Children's Laboratory    

Department

Department:  Chemistry

Location: Chem East

Phone Number: (206) 987-2617 

 

 

Reference Range

  IU/mL
Negative < 4
Equivocal 5-9
Positive > 10

 

Methodology

Method:  Immunoassay on Bioplex 2200

Analytical Volume: 0.4 uL serum

Limitations:

CPT Codes

CPT CODE(S)
86225