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Test Code C1ES C1 Esterase (C1ES) Inhibitor Antigen, Serum

Reporting Name

C1 Esterase Inhibitor Antigen, S

Useful For

Diagnosis of hereditary angioedema

 

Monitoring levels of C1 esterase inhibitor in response to therapy


Specimen Required


Collection Container/Tube:

Preferred: Red top

Acceptable: Serum gel

Submission Container/Tube: Plastic vial

Specimen Volume: 1 mL

Collection Instructions: Fasting preferred but not required.


Specimen Type

Serum

Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Frozen (preferred) 14 days
  Ambient  72 hours
  Refrigerated  72 hours

Day(s) and Time(s) Performed

Monday through Saturday; Continuously until 3 p.m.

Performing Laboratory

Mayo Medical Laboratories in Rochester

Method Name

Nephelometry

Method Description

C1 esterase inhibitor complement antigen (C1ES) is measured by immunonephelometry. Antiserum to C1ES is mixed with patient serum, the light scatter resulting from the antibody interaction with C1ES is measured, and the signal is compared to standard concentrations of C1ES.(Instruction Manual: Siemens Nephelometer II Operations, 2005)

Reference Values

19-37 mg/dL

Test Classification

This test has been cleared or approved by the U.S. Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information

83883

LOINC Code Information

Test ID Test Order Name Order LOINC Value
C1ES C1 Esterase Inhibitor Antigen, S 4477-6

 

Result ID Test Result Name Result LOINC Value
C1ES C1 Esterase Inhibitor Antigen, S 4477-6

Reject Due To

Hemolysis

Mild OK; Gross OK

Lipemia

Mild OK; Gross reject

Icterus

Mild OK; Gross OK

Other

NA