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Test Code D-DIMER D-Dimer

Clinical System Name

D-Dimer
 

Synonyms

D Dimer
DDimer
FDP
Fibrin Degradation Products

Description

This particular test is used in conjunction with other tests (eg. Platelet count, Clauss Fibrinogen, Thrombin Time, and to a lesser extent PT and APTT) to identify patients with DIC.

Sample Requirements

Specimen: Whole Blood

Container(s): Lt Blue/Citrate

Preferred Vol: 1.8 mL

Minimum Vol: N

 

Note:  Preferred method of collection is venipuncture with vacuum fill.  Test results are affected by incorrect blood volume.  Use of a Vascular Access Device for the  collection of coag testing is not recommended.

If this method is used it requires a 5 cc clearing volume; 3 cc for size 2 French catheter or smaller. Blood must be trasferred to the  Lt Blue/Citrate tube by use of a  blood transfer device to ensure proper fill. 

Specimen should be centrifuged within 1 hour of collection.

Processing Instructions

Reject due to: Clotted, Hemolyzed, Insufficient quantity, and  Improper collection.

Spin:N

Aliquot:N

Temp:RT

Storage location: Core 6 Freezer  ( -70 C).

 

Note: Deliver blood to Core Coag bench.  Coag Technologist will process. Specimen should be centrifuged within 1 hour of collection. Spin whole blood, remove plasma. Transfer upper 3/4 layer of plasma to plastic tube affixed with large computer label.

 

 

 

Off-site collection:Preferred method of collection is venipuncture with vacuum fill. Test results are affected by incorrect blood volumel. Use of a Vascular Access Device for the collection of coag testing is not recommended. If this method is used it requires a 5 cc clearing volume; 3 cc for size 2 French catheter or smaller. Blood must be trasferred to the Lt Blue/Citrate tube by use of the blood transfer device.

Specimen should be centrifuged within 1 hour of collection. Double spin, transfer upper 3/4 layer of plasma to plastic tube affixed with large computer label. Freeze 2 aliquots of 1.0 mL plasma in plastic tubes at -70C.

Ship frozen on dry ice.

.

Stability

Specimen Type Temperature Time
Citrated platelet-poor plasma Room temp N
  Refrigerated N
  Frozen   -20 C or -70 C 3 m

 

Availability

STAT Performed TAT
Y

Daily

1 h

 

Performing Laboratory

Seattle Children's Laboratory    

 

Department

Department:  Coagulation

Phone Number: 206 987-2578

 

 

 

Reference Range

<0.5 ug/mL FEU

 

 

 

Methodology

Method:  Latex Agglutination using  the immuno-turbidimetric determination by STA® Compact  Analyzers

Analytical Volume: 1 mL plasma

This is enough for a PT, PTT, TT, and Fibrinogen on the same sample.

 

Limitations: Results affected by moderate lipemia, moderate hemolysis, and moderate icterus.

Method is affected by improper collection, processing and storage.

High hematocrit greater than or equal to 56% requires a citrate adjusted tube.

CPT Codes

85378

Critical Values

Not defined for this test.