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Test Code MPS CSF Q MPS Quant, CSF

Clinical System Name

Mucopolysaccharides Quant, CSF

Synonyms

GAG

Glycosaminoglycans

Description

Quantitation of MPS in CSF by DMB dye binding spectrophotometric method

Sample Requirements

Specimen: CSF

Container(s): Sterile Screw-Capped Container/Tube

Preferred Vol:  1.0 mL

Minimum Vol: 0.5 mL

 

Note: 

Processing Instructions

Reject due to:

Spin:Y

Aliquot:Y

Temp:-20 C

Storage location: BCG Box

 

Off-site collection:  Ship frozen.

Stability

Temperature Time
Room temp ≤24 hrs
Refrigerated  2 d
Frozen  3 wks

 

Availability

STAT Performed TAT
N Twice weekly 7 days

 

 

Performing Laboratory

Seattle Children's Laboratory    

Department

Department:  Biochemical Genetics

Phone Number: 206-987-2216

 

 

Methodology

Method: Spectrophotometric Assay

Analytical Volume:

Limitations: Protein or red cells in CSF can falsely elevated the MPS

CPT Codes

83864

Requisition

Biochemical Genetics Requisition

 

On the requisition include clinical inforamtion needed for appropriate interpretation. (Age, gender, diet (e.g. TPN therapy), drug therapy and family history)

Clinical Utility

In storage disease patients who have had bone marrow transplant or enzyme replacement therapy, CSF may be assayed to assess the efficacy of the treatment on the central nervous system.

Reference Ranges

< 12 mg/L