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Test Code Neurotran Neurotransmitter Metabolites, CSF

Important Note

Specimens collected for this test may also be used for 5-Methyltetrahydrofolate, CSF Neopterin, and/or CSF Tetrahydrobiopterin/Neopterin profile - all performed at the same reference laboratory. Separate CSF specimens should be submitted for all other testing.

Clinical System Name

Neurotransmitter Metabolites, CSF

Sample Requirements

Specimen: Cerebral Spinal Fluid

Container(s): See Comments

Preferred Vol: 4.5 mL

Minimum Vol: 0.5 mL in tube #1 (run risk of not being able to add other testing)

 

Note: Call the Laboratory for appropriate specimen collection containers. Each set consists of 5 numbered microcentrifuge tubes. One complete set of tubes is required per patient. CSF should be collected from the first drop into the tubes in the numbered order. Fill each tube to the marked line. Label tubes with patient name and ID number, leaving the tube number viewable. Place the tubes on ice at the bedside immediately after collection. Hand deliver specimens to the Lab immediately.

Processing Instructions

Reject due to:

Spin:

Aliquot:

Temp: - 70 C

Storage location: LAB ASSISTANTS: Give specimens to send outs department immediately. IF SEND OUTS NOT AVAILABLE: If the sample is blood contaminated, the tubes should immediately be centrifuged and the clear CSF transferred to new similarly labeled tubes. Freeze all 5 specimen tubes together in the -70 freezer send outs rack ASAP after collection.

 

Off-site collection:

Stability

Specimen Type Temperature Time
CSF Room temp N
  Refrigerated N
  Frozen Y

 

Availability

STAT Performed TAT
N Collect  daily; set up M - F  2 - 3 w

 

Performing Laboratory

Medical Neurogenetics

Department

Department:  

Medical Neurogenetics

5424 Glenridge Dr
Atlanta, GA 30342
 

Phone Number: (678) 225-0222 ext 201

 

 

Reference Range

 

 

AGE (years) 5-HIAA nmol/L HVA nmol/L 3-O-MD nmol/L
0 - 0.2 208-1159 337-1299 <300
0.2 - 0.5 179-711 450-1132 <300
0.5 - 2.0 129-520 294-1115 <300
2.0 - 5.0 74-345 233-928 <150
5.0 - 10 66-338 218-852 <100
10 - 15 67-189 167-563 <100
Adults 67-140 145-324 <100

Interpretation provided by reference laboratory

Methodology

Method: HPLC

Analytical Volume: None specified

Limitations:

CPT Codes

82542, 83497, 83150 (TLZ 04/18/16)

Send Out Instructions

 

Reference Test Name: CSF Neurotransmitter Metabolite
Reference Test Number: NCO4
Instructions:

If the sample is blood contaminated, the tubes should immediately be centrifuged and the clear CSF transferred to new similarly labeled tubes. Freeze all 5 specimen tubes together in the -70 freezer send outs rack ASAP after collection. Keep a copy of the requisition for our records.

 

Note: Saturday deliveries are acceptable.