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Test Code PARVO Parvovirus B19 Antibodies, IgG and IgM, Serum

Advisory Information

Serologic evaluation for antibodies to parvovirus B19 is useful in patients with at least 5 to 7 days of symptoms or asymptomatic individuals with recent exposure to parvovirus B19; see PARVP / Parvovirus B19, Molecular Detection, PCR, Plasma or PARVO / Parvovirus B19, Molecular Detection, PCR.

Specimen Required


Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 0.5 mL

Useful For

Serologic detection of recent or past parvovirus B19 infection

Profile Information

Test ID Reporting Name Available Separately Always Performed
PARVG Parvovirus B19 Ab, IgG, S No Yes
PARVM Parvovirus B19 Ab, IgM, S No Yes
PARVN Parvovirus B19 Ab Interpretation No Yes

Method Name

Enzyme Immunoassay (EIA)

Reporting Name

Parvovirus B19 Ab, IgG and IgM, S

Specimen Type


Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Refrigerated (preferred) 14 days
  Frozen  14 days

Reject Due To


Mild OK; Gross reject


Mild OK; Gross reject


Mild OK; Gross reject



Reference Values

IgG: Negative

IgM: Negative

Method Description

Antibody to parvovirus B19 is detected by a sandwich EIA for the detection of IgG or IgM class antibodies in serum or plasma (Biotrin, Dublin, Ireland). Specific parvovirus B19 antibodies in specimens bind to antigen-coated microtiter wells. Following a wash step, peroxidase-labeled rabbit-antihuman IgG is added that binds to parvovirus antibody. The antigen-antibody complex is detected by the addition of substrate, which turns blue in the presence of the enzyme peroxidase.(Anderson LJ, Tsou R, Parker RA, et al: Detection of antibodies and antigens of human parvovirus B19 by enzyme-linked immunosorbent assay. J Clin Microbiol 1986;24[4]:522-526)

Day(s) and Time(s) Performed

Monday through Friday; 11 a.m.

Performing Laboratory

Mayo Medical Laboratories in Rochester

Test Classification

This test has been modified from the manufacturer's instructions. Its performance characteristics were determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.

CPT Code Information

86747 x 2

LOINC Code Information

Test ID Test Order Name Order LOINC Value
PARVS Parvovirus B19 Ab, IgG and IgM, S 34950-6


Result ID Test Result Name Result LOINC Value
PARVG Parvovirus B19 Ab, IgG, S 29660-8
PARVM Parvovirus B19 Ab, IgM, S 40658-7
PARVN Parvovirus B19 Ab Interpretation 58737-8