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Test Code Posaconazole Posaconazole Level

Clinical System Name

Posaconazole Level

Synonyms

Antifungal drug

Noxafil

Sample Requirements

Specimen: Whole blood

Container(s): Red or Dark Green/Sodium Heparin

Preferred Vol:1 mL

Minimum Vol: 1 mL

 

Note: Please allow a minimum of 72 h after starting or changing a dose before drawing a Posaconazole level. Draw trough level 30-60 min before next dose. Microtainers and gel separators are unacceptable.

 

Processing Instructions

Reject due to: Serum/plasma separator tubes

Spin: Y

Aliquot:Y

Temp: - 20 C

Storage location: Freeze 0.4 mL serum/plasma in CPA Freezer, Fz5 rack.

 

Off-site collection: Transfer 0.4 mL serum/plasma in plastic tube and store and send frozen.

Stability

Specimen Type Temperature Time
serum/plasma Room temp 1 d
  Refrigerated 1 w
  Frozen 6 m

 

Availability

STAT Performed TAT
N M-F M-F: Same day if received by 10:00; 1-3 d

 

Performing Laboratory

Seattle Children's Laboratory    

 

Department

Department:  Chemistry

Location: Chem West

Phone Number: (206) 987-2617

 

 

 

Reference Range

Trough therapuetic range >/= 700 ng/mL

 

 

Posaconazole levels of  >500 ng/mL have been shown to be effective for prophylaxis management.

 

Methodology

Method: LC/MS/MS

Analytical Volume: 0.25 mL serum/plasma

Limitations:

CPT Codes

80299