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Test Code Q FEVER Q Fever Antibody, IgG and IgM, Serum

Reporting Name

Q Fever Ab, IgG and IgM, S

Useful For

Diagnosing Q fever


Specimen Required


Container/Tube: 

Preferred: Serum gel

Acceptable: Red top

Specimen Volume: 0.5 mL


Specimen Type

Serum

Specimen Minimum Volume

0.25 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Refrigerated (preferred) 7 days
  Frozen  7 days

Day(s) and Time(s) Performed

Monday through Friday; 9 a.m.

Performing Laboratory

Mayo Medical Laboratories in Rochester

Method Name

Indirect Immunofluorescence

Method Description

An indirect immunofluorescence test is used for the measurement of IgM and/or IgG antibodies to Coxiella burnetii. Specific antibodies present in the serum of the patient react with rickettsial cells that have been previously fixed on a glass microscope slide. Fluorescein-labeled antihuman IgG or IgM conjugate is used to stain specific antibody bound to the substrate cells. The slides are examined with a fluorescence microscope for characteristic, apple-green fluorescence of the infected cell.(Edligner B: Immunofluorescence serology: a tool for prognosis of Q fever Diagn Microbiol Infect Dis 1985;3:343-351; Package inserts: Q fever IFA IgG Focus Diagnostics, Inc., Cypress, CA; Q fever IFA IgM, Focus Diagnostics, Inc., Cypress, CA)

Reference Values

Q FEVER PHASE I ANTIBODY, IgG

<1:16

 

Q FEVER PHASE II ANTIBODY, IgG

<1:16

 

Q FEVER PHASE I ANTIBODY, IgM

<1:16

 

Q FEVER PHASE II ANTIBODY, IgM

<1:16

Test Classification

This test has been cleared or approved by the U.S. Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information

86638 x 4

LOINC Code Information

Test ID Test Order Name Order LOINC Value
QFP Q Fever Ab, IgG and IgM, S In Process

 

Result ID Test Result Name Result LOINC Value
80965 Q Fever Phase I Ab, IgG 34716-1
24011 Q Fever Phase II Ab, IgG 34717-9
81115 Q Fever Phase I Ab, IgM 9710-5
24009 Q Fever Phase II Ab, IgM 9711-3
24010 Interpretation 69048-7

Reject Due To

Hemolysis

Mild OK; Gross reject

Lipemia

Mild OK; Gross reject

Icterus

NA

Other

NA

Testing Algorithm

See Infective Endocarditis: Diagnostic Testing for Identification of Microbiological Etiology in Special Instructions.