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Test Code RENIN Renin

Clinical System Name

Renin

Synonyms

Plasma Renin Activity
PRA (Plasma Renin Activity)
 

Sample Requirements

Specimen: Whole Blood

Container(s): Lavender/EDTA

Preferred Vol: 4 mL

Minimum Vol: 2.4 mL

 

Note: SUPINE: Obtain sample 8-10 AM, fasting starting at midnight, on a normal sodium diet (100-200 mEq/day).

UPRIGHT: Samples obtained before noon (after at least 2 hours in upright position), on a normal sodium diet.

Processing Instructions

Reject due to: Hemolyzed or refrigerated specimens

Spin: Y

Aliquot: Y

Temp: -20 C

Storage location: CPA -20 freezer, critical frozen, spun plasma must be frozen within two hours of collection.

 

Off-site collection: Separate from cells ASAP or within two hours of collection and freeze immediately.

Stability

Specimen Type Temperature Time
Plasma (after separation from cells) Room temp

6 h

  Refrigerated N
  Frozen

4 w

 

Availability

STAT Performed TAT
N Drawn daily, performed daily 2 - 4 d

 

Performing Laboratory

ARUP Laboratories

500 Chipeta Way
Salt Lake City, UT 84108-1221
 

Phone Number: (800) 522-2787

Department

Department:  Send Outs

 

Phone Number: (206) 987-2563

 

Reference Range

 

Age Supine (ng/mL/hr) Upright (ng/mL/hr)
Newborn (1 - 7 days) 2.0 - 35.0 NA
Cord Blood 4.0 - 32.0 NA
1 - 12 months 2.4 - 37.0 NA
13 months - 3 years 1.7 - 11.2 NA
4 - 5 years 1.0 - 6.5 ≤15
6 - 10 years 0.5 - 5.59 ≤17
11 - 15 years 0.5 - 5.9 ≤16
Adult 0.2 - 1.6 0.5 - 4.0

Plasma renin activity measures enzyme ability to convert angiotensinogen to angiotensin I and is limited by the availability of angiotensinogen. Plasma renin activity is not an accurate indicator of enzyme activity when angiotensinogen is decreased.
 

 

Methodology

Method: Radioimmunoassay

Analytical Volume: None specified

Limitations:

CPT Codes

84244 (TLZ 05/17/16)

 

Send Out Instructions

 

Reference Test Name: Renin Activity
Reference Test Number:

0070105

Instructions:

Send out M - F with ARUP courier.