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Test Code Silver Silver, Serum

Reporting Name

Silver, S

Useful For

Determination of silver exposure

Specimen Required

Patient Preparation: High concentrations of gadolinium and iodine are known to interfere with most metals tests. If either gadolinium- or iodine-containing contrast media has been administered, a specimen should not be collected for 96 hours.


Metal Free B-D Tube (No Additive), 6 mL (T184)

Metal Free Specimen Vial (T173)

Collection Container/Tube: Plain, royal blue-top Vacutainer plastic trace element blood collection tube (T184)

Submission Container/Tube: 7-mL Mayo metal-free, screw-capped, polypropylene vial (T173)

Specimen Volume: 1.6 mL

Collection Instructions:

1. Allow the specimen to clot for 30 minutes; then centrifuge the specimen to separate serum from the cellular fraction.

2. Remove the stopper. Carefully pour specimen into Mayo metal-free, polypropylene vial, avoiding transfer of the cellular components of blood. Do not insert a pipet into the serum to accomplish transfer, and do not ream the specimen with a wooden stick to assist with serum transfer.

3. See Trace Metals Analysis Specimen Collection and Transport in Special Instructions for complete instructions.

Additional Information: If ordering the trace element blood collection tube from BD, order catalog #368380.

Seattle Children's Hospital Note:

Processing Note: Use of a standard pipette is acceptable for aliquoting these samples.

Specimen Type


Specimen Minimum Volume

0.4 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Refrigerated (preferred) 28 days
  Frozen  28 days
  Ambient  14 days

Day(s) and Time(s) Performed

Wednesday; 8 a.m.

Performing Laboratory

Mayo Medical Laboratories in Rochester

Method Name

Inductively Coupled Plasma-Mass Spectrometry (ICP-MS)

Method Description

Silver in serum is analyzed by inductively coupled plasma-mass spectrometry (ICP-MS) in standard mode using indium (In) as an internal standard and a matrix matched calibration.(Unpublished Mayo method)

Reference Values

<15 ng/mL

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.

CPT Code Information


LOINC Code Information

Test ID Test Order Name Order LOINC Value
AGS Silver, S 5734-9


Result ID Test Result Name Result LOINC Value
8607 Silver, S 5734-9

Reject Due To


Mild OK; Gross OK


Mild OK; Gross OK


Mild OK; Gross reject