Sign in →

Test Code U MPS4Mon MPS IV Monitoring, Urine

Clinical System Name

MPS IV Monitoring, Urine


Keratan Sulfate, Urine

Morquio Syndrome Monitoring, Urine

Sample Requirements

Specimen: Urine

Container(s): Sterile Screw-Capped Container

Preferred Vol: 5 mL

Minimum Vol: 3 mL



Processing Instructions

Reject due to:

Spin: Y/N

Aliquot: Y/N

Temp: Frozen

Storage location: Place urine aliquot container in sendouts freezer


Off-site collection: Send urine frozen.


Specimen Type Temperature Time
  Room temp  
  Frozen Y



STAT Performed TAT
N   10 d


Performing Laboratory

Greenwood Genetic Center


Department: Greenwood Genetic Center, 106 Gregor Mendel Circle Greenwood, SC 29646

Phone Number: 1 (888) GGC-GENE

Reference Range

Total GAGs 0-16 mg/mmol creatinine
Chondr Sulfate 0-11.21 g/mol creatinine
Kerat Sulf 0-9.6 mcg/mg creatinine



Method: Quantitative analysis of total glycosaminoglycans (GAGs) is performed using a 1,9-dimethylene blue (DMB) colorimetric reaction that is measured by spectrophotometry at a wavelength of 656 nm. GAG measurements are reported relative to the creatinine concentration in the patient's urine.

Quantification of individual glycosaminoglycans -chondroitin sulfate (uCS), dermatan sulfate (uDS), heparan sulfate (uHS), and keratan sulfate (uKS)- is performed using liquid chromatography-tandem mass spectrometry.

Analytical Volume:


CPT Codes

83864 X 2

Send Out Instructions

Reference Test Name: Mucopolysaccharide Monitoring, Urine
Reference Test Number: MPS IV (Total GAGs, KS, CS)

Ship frozen samples overnight via FedEx to Greenwood Genetics.


Note: Saturday deliveries are acceptable.