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Test Code Mono Scr Mono Screen

Clinical System Name

Infectious Mono Screen


Heterophile Antibody

Heterophile Screen


A rapid screen used to confirm the diagnosis of infectious mononucleosis.

Sample Requirements

Specimen: Whole Blood

Container(s):  Gold SST, Red, Gold Microtainer, Lavander/EDTA

Preferred Vol:  1.0 mL

Minimum Vol:  0.5 mL


Notes: Heparinized plasma is unacceptable.


A heterophile antibody response is only observed in  approximately 50% of children 4 years of age and younger.

Processing Instructions

Reject due to:  Insufficient Quantity, Heparinized plasma

Spin: Y

Aliquot: Y

Temp:  2-8oC

Storage location: Core 5 Refrigerator.


SCH: Samples should be given to Core Lab.


Regional Clinics: Samples should be given to Regional Clinic Lab.


Non-Children's Hospital Off-site collection: Spin blood, separate serum/EDTA plasma from cells. Send refrigerated (2-8oC).



Specimen Type Temperature Time
Serum or Plasma RT

4 H

Serum or Plasma 2-8oC

48 H

Serum or Plasma -20oC or -70oC

3 M



STAT Performed TAT
Y 24/7 1 H


Performing Laboratory

Seattle Children's Laboratory    


Department:  Core Chemistry

Phone Number: 206-987-2617



Reference Range




Method:  Color immunochromatographic dipstick technology with bovine erythrocytes

Analytical Volume:  0.1 mL serum or EDTA plasma

CPT Codes