Sign in →

Test Code RENIN Renin

Clinical System Name

Renin

Synonyms

Plasma Renin Activity

PRA

Renin Activity, Plasma
 

Sample Requirements

Specimen: Whole Blood

Container(s): Lavender/EDTA

Preferred Vol: 4.0 mL

Minimum Vol: 2.4 mL

 

Note: SUPINE: Obtain sample 8-10 AM, fasting starting at midnight, on a normal sodium diet (100-200 mEq/day).

UPRIGHT: Samples obtained before noon (after at least 2 hours in upright position), on a normal sodium diet.

Processing Instructions

Reject due to: Serum. Specimens collected in citrate, heparin, or oxalate. Hemolyzed specimens.

Spin: Y

Aliquot: Y

Temp: -20 C

Storage location: CRITICAL FROZEN. Spun plasma must be frozen within two hours of collection. Place the aliquot in the CPA -20 freezer, Send Outs rack.

 

Off-site collection: Separate from cells ASAP or within two hours of collection and freeze immediately.

Stability

Specimen Type Temperature Time
Plasma (after separation from cells) Room temp

6 h

  Refrigerated Unacceptable
  Frozen

1 m

 

Availability

STAT Performed TAT
N Daily 1 - 3 d

 

Performing Laboratory

ARUP Laboratories

500 Chipeta Way
Salt Lake City, UT 84108-1221

 

Phone Number: (800) 522-2787

Department

Department: Send Outs

Phone Number: (206) 987-2563

 

Reference Range

Age Supine (ng/mL/hr) Upright (ng/mL/hr)
Newborn (1 - 7 days) 2.0 - 35.0 NA
Cord Blood 4.0 - 32.0 NA
1 - 12 months 2.4 - 37.0 NA
13 months - 3 years 1.7 - 11.2 NA
4 - 5 years 1.0 - 6.5 ≤15
6 - 10 years 0.5 - 5.59 ≤17
11 - 15 years 0.5 - 5.9 ≤16
Adult 0.2 - 1.6 0.5 - 4.0

Plasma renin activity measures enzyme ability to convert angiotensinogen to angiotensin I and is limited by the availability of angiotensinogen. Plasma renin activity is not an accurate indicator of enzyme activity when angiotensinogen is decreased.
 

 

Methodology

Method: Quantitative Enzyme-Linked Immunosorbent Assay

Analytical Volume: 1.2 mL

Limitations:

CPT Codes

84244

Send Out Instructions

Reference Test Name: Renin Activity
Reference Test Number:

0070105

Instructions:

Send out Monday - Friday with the ARUP courier.