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Test Code TwinZyg Twin Zygosity Testing

Clinical System Name

Twin Zygosity Testing

Synonyms

Zygosity Testing

Fetal Zygosity

Mono/Dizygotic Differentiation

Newborn Zygosity

Zygosity, Twin Pre/Postnatal

Sample Requirements

Specimen: Whole Blood

Container(s): From each twin: Lavender/EDTA, Yellow/ACD A, or Yellow/ACD B

Preferred Vol: From each twin: 3 mL

Minimum Vol: From each twin: 2 mL

 

Specimen: Buccal Swab

Container(s): From each twin: Sterile Screw-Capped Container

Preferred Vol: From each twin: 2 Buccal Swabs

Minimum Vol: From each twin: 2 Buccal Swabs

 

Note: Collect TWO buccal swabs from each twin. Label the container(s) appropriately.

1-3 mL whole blood in Lavender/EDTA  or Yellow/ACD A or B also acceptable. Blood must be collected from BOTH twins.

Processing Instructions

Reject due to: Frozen specimens.

Spin: N

Aliquot: N

Temp: 2 - 4 C

Storage location: Deliver swabs in container(s) to CPA refrigerator, Send Outs rack. Do not spin blood, deliver to CPA refrigerator, Send Outs rack.

 

Off-site collection: Do not spin whole blood. Refrigerate swabs or whole blood.

Stability

Specimen Type Temperature Time
Whole Blood or Buccal Swab Room temp

72 h

  Refrigerated 1 w
  Frozen

Unacceptable

 

Availability

STAT Performed TAT
N Varies 5 - 10 d

 

Performing Laboratory

ARUP Laboratories

500 Chipeta Way
Salt Lake City, UT 84108-1221

 

Phone Number: (800) 522-2787

Department

Department: Send Outs

 

Phone Number: (206) 987-2563

 

Reference Range

Monozygotic Twins Greater than 99% certainty (all markers match)
Dizygotic Twins 99% certainty (two or more markers do not match)

 

Methodology

Method: Polymerase Chain Reaction/Fragment Analysis

Analytical Volume: 1 mL Whole Blood or 2 Buccal Brushes

Limitations:

Special Instructions

Links to:

 

ARUP

 

 

Send Out Instructions

Reference Test Name: Twin Zygosity Testing
Reference Test Number:

0050547

Instructions:

Send out Monday - Friday with the ARUP courier.