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Test Code URIC Uric Acid

Important Note

If the patient is receiving Rasburicase, the sample must be placed in a separate bag, then  into a bag with ice.

Clinical System Name

Uric Acid


Uric acid is the end product of purine metabolism.  Elevations of uric acid occur in renal failure, prerenal azotemia, gout, lead poisoning, excessive cell destruction (e.g., following chemotherapy), hemolytic anemia, myocardial infarction,  congestive heart failure, endocrine disorders, acidosis, and glycogen storage disease type I.  Low uric acid concentration may be found following treatment by some drugs (e.g., low dose aspirin), low dietary intake of purines, renal tubular defects, and in xanthinuria.

Sample Requirements

Specimen:  Whole Blood

Container(s): Gold SST, Dark Green/Sodium Heparin, Red

Preferred Vol:  0.5 mL

Minimum Vol: 1 Gold Microtainer or 1 Lt. Green/Li Heparin Microtainer


Note:  Method is affected by EDTA, Sodium Fluoride, Sodium Citrate, and gross hemolysis. 


Processing Instructions

Reject due to: Insufficient quantity, incorrect specimen type, Rasburicase patient samples not arriving on ice

Spin: Y

Aliquot: Y

Temp: 2-4oC

Storage location: Core Chemistry Refrigerator

Notes: Spin specimens received on ice in the refrigerated centrifuge and deliver to Core Cell immediately.


Off-site collection:  Spin blood, remove plasma or serum from cells. Refrigerate (2-4oC ). Refrigerated samples are stable for 5 days.


Specimen Type Temperature Time
Serum or Plasma RT

≤ 3 D

Serum or Plasma  2-4oC

≤ 5 D

Serum or Plasma -20oC or -70oC

≤ 6 M



STAT Performed TAT
Y 24/7 1 H


Performing Laboratory

Seattle Children's Laboratory    


Department:  Core Chemistry

Phone Number: 206-987-2617



Reference Range


0 - 18 years 2.0 - 6.0
Female > 18 Y 2.0 - 6.0
Male > 18 Y 2.0 - 7.0



Method:  Colorimetric method by Vitros 4600

Minimum Volume: 0.05 mL serum or plasma

Analytical Volume:  0.01 mL + 0.03 mL dead space


CPT Codes