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Test Code VISCS Viscosity, Serum

Reporting Name

Viscosity, S

Useful For

Detection of increased viscosity


Monitoring patients with hyperviscosity syndrome

Specimen Required

Container/Tube: Red top

Specimen Volume: 1.5 mL

Collection Instructions: Keep specimen at 37° C (eg, 37° C Thermopak, heat block) until after centrifugation and separation of cells.

Specimen Type

Serum Red

Specimen Minimum Volume

0.65 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Red Refrigerated (preferred) 14 days
  Ambient  14 days
  Frozen  14 days

Day(s) and Time(s) Performed

Monday through Friday; Continuously until 2 p.m.

Performing Laboratory

Mayo Medical Laboratories in Rochester

Method Name

Sonoclot Coagulation Analyzer

Method Description

The viscosity is measured with a Sonoclot Coagulation Analyzer (Sienco, Inc., Wheat Ridge, CO). The instrument measures the power required to oscillate a probe at a constant rate. The increased power required in sera with increased viscosity is calibrated by standards of known viscosity.(Chandler WL, Schmer S: Evaluation of a new dynamic viscometer for measuring the viscosity of whole blood and plasma. Clin Chem 1986;32/3:505-507)

Reference Values

≥16 years: ≤1.5 centipoises

Reference values have not been established for patients that are <16 years of age.

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the U.S. Food and Drug Administration.

CPT Code Information


LOINC Code Information

Test ID Test Order Name Order LOINC Value
VISCS Viscosity, S 3128-6


Result ID Test Result Name Result LOINC Value
8168 Viscosity, S 3128-6

Reject Due To


Mild OK; Gross OK


Mild OK; Gross OK


Mild OK; Gross OK


Serum gel tube


If not ordering electronically, complete, print, and send the following form with the specimen:

Hematopathology/Cytogenetics Test Request Form (T726) (