Home
HelpCilia Biopsy, Histo/Path
Clinical System Name
Surgical Pathology Final Report
Synonyms
Ciliary Biopsies
Sample Requirements
Specimen: Nasal epithelium preferred; nasopharyngeal epithelium accepted; see note below
Container(s): see below
Preferred Vol: see below
Minimum Vol: visible on brush
Note: Appropriate specimen type is nasal mucosal brushing/biopsy from the inferior nasal turbinates, or bronchoscopy brushing/biopsy. Brushings are obtained with a 1 mm x 10 mm bronchoscopy brush. Sample should be of sufficient volume to be visible on brush. Cut off the tip of the brush to approximately 5 mm and place directly into a vial containing 10 mL 3% glutaraldehyde obtained from the histology laboratory. Ensure that the brush or biopsy is immersed in fixative. Do not invert vial, as brush must remain immersed in fixative. HAND CARRY TO LAB IMMEDIATELY.
Comment: Cilia fixative (3% glutaraldehyde) is prepared in Histology Lab (FB.4.555) 987-2580. Fixative must be picked up from Histology Lab and specimens returned to Histology Lab as soon as possible. Optimally, the patient should be free of upper respiratory infection and congestion at the time of biopsy.
Processing Instructions
Reject due to:
Spin: N
Aliquot: N
Temp: Transport at room termperature; refrigerate while stored in lab
Note: Notify Histology immediately when specimen arrives in Lab. Specimen should be labeled with a valid Tissue Pathology Exam sticker. Contact on-call pathologist if Histology is unavailable.
Off-site collection: Specific handling instructions may be obtained from Histology at (206) 987-2580.
Stability
| Specimen Type | Temperature | Time |
|---|---|---|
| Tissue | Room temp | |
| Refrigerated | ||
| Frozen |
Availability
| STAT | Performed | TAT |
|---|---|---|
| M-F 8 a.m. - 5 p.m. | 1-2 weeks |
Performing Laboratory
Seattle Children's Laboratory
Department
Department: Histology
Phone Number: (206) 987-2580; for results inquiries call (206) 987-2103.
CPT Codes
CPT codes will vary depending on tests performed. Call Client Services for more information (206) 987-2617.
Methodology
Method: Electron microscopic examination
Analytical Volume: n/a
Limitations: Concurrent infection can interfere with interpretation
Description
Electron microscopic analysis of structural integrity of cilia, typically in setting of dyskinesia.