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Tests Not Offered at Seattle Children's

Important Note

The following tests are no longer orderable at Seattle Children's Hospitals and Regional Clinics.  These tests have been reviewed the the Laboratory Stewardship Committee, and have been found to have limited clinical utility or insufficient clinical validation.

Sample Requirements

Phlebotomists: Do not collect blood for these tests. 

Notify ordering provider that this test is no longer available at Seattle Children's and we do not send this test out to other reference laboratories. Our Laboratory Stewardship Team has determined that there is no proven, evidence-based clinical utility for the following tests.

 

If a provider wishes to discuss testing options further, a clinical pathologist or doctoral level consultant can be reached through Lab Client Services, or at clinicallabfaculty@seattlechildrens.org.

Clinical Utility

Test Name Recommended Alternative Test(s) Notes/Reference(s)
Adenovirus Antibody Adenovirus culture; Adenovirus PCR  
Antimony, Blood N/A Testing requires glass collection tubes which are not stocked at SCH.
Candida Antibody N/A  
Catecholamines, plasma or urine Metanephrines, plasma or urine Nat Clin Pract Endocrinol Metab, Feb 2007, 3(2):92-102
CD57 for Lyme Disease Lyme Disease Serology

Natural Killer Cell Counts Are Not Different between Patients withPost-Lyme Disease Syndrome and Controls. Clinical and Vaccine Immunology. 2009; 16(8):1249-50.https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2725528/pdf/0167-09.pdf 
Creatine kinase MB (CK-MB) High sensitivity Troponin

CK-MB is no longer widely recommended for cardiac injury, since there are more specific assays available. 
Coxsackie A IgG Entero/Parechovirus PCR Qual Coxsackie A is prevalent in the environment and >60% of individuals over 1-year of age are sero-positive. If an active infection is suspected, PCR testing for the virus is recommended. Hand, foot and mouth disease: seroprevalence of Coxsackie A16 and Enterovirus 71 in Germany | SpringerLink
Echovirus Antibodies Enterovirus PCR panel  
Eosinophil Cationic Protein N/A ECP is a marker of eosinophilic inflammation, although it provides no information about the presence of IgE-mediated allergy.  Not recommended for routine clinical use.
Folate Receptor Antibody Test (F.R.A.T.)    

Gastrointestinal Profile, Stool, PCR

LabCorp Test Code: 183480
  • Rapid Stool Infectious Diarrhea PCR Panel (LAB2451)
  • C. diff Antigen and Toxin by EIA, plus Reflex PCR (LAB2535)
  
Total Glutathione    
H. Pylori Serologies H. Pylori antigen, stool http://www.choosingwisely.org/clinician-lists/american-society-clinical-pathology-serology-for-h-pylori/
Human herpes virus 6 (HHV6) IgG HHV6 by PCR Human herpes virus 6 is prevalent in the environment and seroprevlance rates are nearly universal and rarely pathogenic, unless an individual is immunocompromised. If there are concerns about an active infection, recommend PCR testing to evaluate. HHV-6A, 6B, and 7: persistence in the population, epidemiology and transmission - Human Herpesviruses - NCBI Bookshelf (nih.gov)
Melanocyte Stimulating Hormone N/A Clinical significance is not well understood; research use only.

Metal and Trace Element RBC Testing:

Recommended Alternative Test(s):

Notes/References for Metal and Trace Element RBC Testing:

 

Folate, RBC: Clin Chem Lab Med. 2013;51(3):555-69. doi: 10.1515/cclm-2012-0639.
MTHFR N/A American College of Medical Genetics and Genomics Practice Guideline: lack of evidence for MTHFR polymorphism testing, Genet Med 2013:15(2):153–156
Myelin Basic Protein (MBP) Oligoclonal Band Profile Arch Neurol. 2005; 62(6): 865-70
OmegaCheck Fatty Acid Profile for nutritional monitoring Cleveland Heart Labs is not on approved lab list.  
T3 Uptake TSH and Free T4 ATA/AACE Guidelines for Hypothyroidism in Adults, Endocr Pract. 2012; 18 (6)
Transforming Growth Factor, Beta N/A Immunoflamatory mediator; clinical significance is not well understood; research use only.

 

Last Updated

This list was last reviewed by the Lab Stewardship Committee on March 1st, 2024.