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Heart Biopsy, Histo/Path

Important Note

Cardiologist must notify Histology (206) 987-2580 at least 24 hours in advance.  Weekend biopsies should be discussed beforehand with pathologist on call. FRESH (unfixed) sample should be deliver immediately to Histology. 

Clinical System Name

Surgical Pathology Final Report


Biopsy, heart

Endomyocardial biopsy

Transplant heart biopsy


Endomyocardial biopsies obtained from the right ventricle are procured to assess the etiology for altered heart function in native or allograft hearts.  Tissue undergoes routine processing with the addition of EM, PCR or culture, as necessitated by clinical setting.

Sample Requirements

Specimen:  Tissue

Container(s):  Saline-moistened telfa in sterile specimen container

Preferred Vol:  n/a

Minimum Vol:  n/a


Note:  FRESH (no fixative) heart biopsy must be delivered immediately to 8th floor lab CPA or Histology (OC.8.901) and given to someone's personal charge; identify it as a fresh specimen.  Specific handling instructions may be obtained from Histology at (206) 987-2580.


A completed surgical pathology request form including hospital number, name, date of birth, date of procedure, and a completed heart biopsy worksheet  must be submitted with the specimen. 


After 1700, deliver specimens to the 8th floor lab CPA. . 

Processing Instructions

Reject due to: NA

Spin:  N

Aliquot:  N

Temp: RT

Note:  Notify Histology immediately when specimen arrives in Lab.  Contact on-call pathologist (206) 987-2131 if Histology is unavailable. 


Off-site collection:  Specific handling instructions may be obtained from Histology at (206) 987-2580.


Specimen Type Temperature Time
Tissue Room temp 10 min
  Refrigerated 30 min
  Frozen N



STAT Performed TAT
  M-F 8 a.m. - 5 p.m. 1 day


Performing Laboratory

Seattle Children's Laboratory  


Department:  Pathology/Histology

Phone Number: (206) 987-2580; for results inquiries call (206) 987-2103.




Method: Varies; routine formalin fixation with paraffin embedding and standard sectioning

Analytical Volume:  n/a

CPT Codes

CPT codes will vary depending on tests performed.  Call Client Services for more information (206) 987-2617.


Heart biopsy worksheet.