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HelpOncology SNP Microarray
Clinical System Name
Chromosomal SNP Microarray
Synonyms
Bone Marrow Array
CMA Array
Microarray
Leukemia
Oncology SNP Array
Oncology Array
Single Nucleotide Polymorphism
Description
This test is appropriate for individuals with newly diagnosed acute leukemia
Sample Requirements
Specimen: Whole blood, or bone marrow
Container(s): sodium heparin or Lavender/EDTA
Preferred Vol: 2-3 mL*
Minimum Vol: 0.5-2 mL*
*volume requirement depends on WBC count and can be variable.
Processing Instructions
Reject due to: do not reject, contact Cytogenetics 987-3961
Spin: N
Aliquot: N
Temp: RT
Storage location: Days: Transport specimen, requistion, and labels to 4th floor Cytogenetics (station #181).
Eves/Nights: Store specimen, copy of requisition, and labels in the Cytogenetics box in CPA.
Off-site collection: Ship overnight at RT. Samples received Mon-Fri: 8:00 am - 5:00 pm.
Stability
| Temperature | Time |
|---|---|
| Room temp | 5 days |
| Refrigerated | 5 days |
| Frozen | No |
Availability
| STAT | Performed | TAT |
|---|---|---|
| N | Daily | up to 21 days |
Performing Laboratory
Seattle Children's Hospital
Department
Department: Cytogenetics Laboratory
Phone number: 206-987-3961
Lab Client Services: 206-987-2617, labclientservices@seattlechildrens.org
Lab Genetic Counselors: LabGC@seattlechildrens.org
CPT Codes
81229
Methodology
Method:
The Affymetrix Cytoscan DX array contains 1.9 million non-polymorphic markers and 750,000 SNP markers which gives the following coverage:
- Covering >36,000 RefSeq genes with one/880 bases
- Backbone (non-gene) coverage of one marker/1,700 bases
- X-chromosome genes (one marker/486 bases)
- Covering 12,000 OMIM genes (~one marker/659 bases)