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Oncology SNP Microarray

Important Note

This test will be ordered by cytogenetics laboratory staff as part of the routine cytogenetics work-up of patients with newly diagnosed acute leukemia

Clinical System Name

Chromosomal SNP Microarray

Description

This test is appropriate for individuals with newly diagnosed acute leukemia

Sample Requirements

Specimen: Whole blood, or bone marrow

Container(s): sodium heparin or Lavender/EDTA

Preferred Vol: 2-3 mL*

Minimum Vol: 0.5-2 mL*

*volume requirement depends on WBC count and can be variable.

Processing Instructions

Reject due to: do not reject, contact Cytogenetics 987-3961

Spin: N

Aliquot: N

Temp: RT

Storage location:  Days: Transport specimen, requistion, and labels to 4th floor Cytogenetics (station #181). 

Eves/Nights: Store specimen, copy of requisition, and labels in the Cytogenetics box in CPA.

 

Off-site collection:  Ship overnight at RT. Samples received Mon-Fri: 8:00 am - 5:00 pm.

Stability

Temperature Time
Room temp 5 days
Refrigerated 5 days
Frozen No

 

Performing Laboratory

Seattle Children's Hospital

Department

Department: Cytogenetics Laboratory

Phone number: 206-987-3961

 

Lab Client Services: 206-987-2617, labclientservices@seattlechildrens.org

 

Lab Genetic Counselors: LabGC@seattlechildrens.org

 

 

Synonyms

Bone Marrow Array
CMA Array
Microarray

Leukemia

Oncology SNP Array

Oncology Array
Single Nucleotide Polymorphism

Availability

STAT Performed TAT
N Daily up to 21 days

 

Methodology

Method: 

The Affymetrix Cytoscan DX array contains 1.9 million non-polymorphic markers and 750,000 SNP markers which gives the following coverage:

 

  • Covering >36,000 RefSeq genes with one/880 bases
  • Backbone (non-gene) coverage of one marker/1,700 bases
  • X-chromosome genes (one marker/486 bases)
  • Covering 12,000 OMIM genes (~one marker/659 bases)

CPT Codes

81229

Special Instructions

Pre-test counseling