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Oncology SNP Array

Important Note

This test will be ordered by cytogenetics laboratory staff as part of the routine cytogenetics work-up of patients with newly diagnosed acute leukemia

Clinical System Name

Cytogenetics Oncology SNP Array Request

Synonyms

Affymetrix
Array

Bone Marrow Array
CMA Array
Cytoscan Array
Microarray

Leukemia

Acute Leukemia

Oncology SNP Array
Single Nucleotide Polymorphism
SNP
SNP Array

ThermoFisher

Description

This test is appropriate for individuals with newly diagnosed acute leukemia

Sample Requirements

Specimen: Whole blood, or bone marrow

Container(s): sodium heparin or Lavender/EDTA

Preferred Vol: 2-3 mL*

Minimum Vol: 0.5-2 mL*

*volume requirement depends on WBC count and can be variable.

Processing Instructions

Reject due to: do not reject, contact Cytogenetics 987-3961

Spin: N

Aliquot: N

Temp: RT

Storage location:  Days: Transport specimen, requistion, and labels to 10th floor Cytogenetics (station #180). 

Eves/Nights: Store specimen, copy of requisition, and labels in the Cytogenetics box in CPA.

 

Off-site collection:  Ship overnight at RT. Samples received Mon-Fri: 8:00 am - 5:00 pm.

Stability

Temperature Time
Room temp 5 days
Refrigerated 5 days
Frozen No

 

Availability

STAT Performed TAT
N Daily up to 21 days

 

Performing Laboratory

Seattle Children's Hospital

Department

Department: Cytogenetics Laboratory

Phone number: 206-987-3961

 

Lab Client Services: 206-987-2617, labclientservices@seattlechildrens.org

 

Lab Genetic Counselors: LabGC@seattlechildrens.org

 

 

Methodology

Method: 

The Affymetrix Cytoscan DX array contains 1.9 million non-polymorphic markers and 750,000 SNP markers which gives the following coverage:

 

  • Covering >36,000 RefSeq genes with one/880 bases
  • Backbone (non-gene) coverage of one marker/1,700 bases
  • X-chromosome genes (one marker/486 bases)
  • Covering 12,000 OMIM genes (~one marker/659 bases)

CPT Codes

81229

Special Instructions

Pre-test counseling