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HelpD-Lactate, Urine
Reporting Name
D-Lactate, UUseful For
Preferred test for diagnosing D-lactate acidosis, especially in patients with jejunoileal bypass and short-bowel syndrome
Specimen Required
Container/Tube: Plastic, 10-mL urine tube (T068)
Specimen Volume: 2.5 mL
Collection Instructions:
1. Collect a timed or random urine specimen.
2. No preservative.
3. Immediately freeze specimen.
Specimen Type
UrineSpecimen Minimum Volume
0.65 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Urine | Frozen (preferred) | 365 days | |
| Refrigerated | 7 days | ||
| Ambient | 72 hours |
Day(s) Performed
Wednesday, Friday
TAT: 6 - 10 days
Performing Laboratory
Mayo Clinic Laboratories in Rochester
Method Name
Enzymatic
Method Description
D-lactate is oxidized to pyruvate in the presence of D-lactate dehydrogenase and nicotinamide adenine dinucleotide (NAD+). The reaction proceeds because the pyruvate is continually removed as a pyruvate-hydrazone complex. The quantity of NADH produced is directly proportional to the amount of D-lactate oxidized and is measured spectrophotometrically at 340 nm.(Unpublished Mayo method based on Brandt approach[1])
Reference Values
0.0-0.25 mmol/L
Test Classification
This test was developed, and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. This test has not been cleared or approved by the US Food and Drug Administration.CPT Code Information
83605
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| DLAU | D-Lactate, U | 14046-7 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 8873 | D-Lactate, U | 14046-7 |