Sign in →

Test Code FACTOR 11 Factor 11 Assay

Important Note

Method is affected by hemolysis and improper specimen handling. Patients on Direct Thrombin Inhibitors (Novastan, argatroban, bivalirudin) may show prolonged clotting times due to the direct thrombin inhibition. This may cause an under-estimation of the factor concentrations.

Clinical System Name

Factor 11 Assay

Synonyms

Factor 11 Activity
Factor XI Activity

Sample Requirements

Specimen: Whole Blood

Container(s): Lt. Blue/Citrate

Preferred Vol: (1) 2.7 mL

Minimum Vol: (1) 1.8 mL

 

Note: Preferred method of collection is venipuncture with vacuum fill.  Test results are affected by incorrect blood volume. Use of a Vascular Access Device for the  collection of coag testing is not recommended.

If this method is used it requires a 5 cc clearing volume; 3 cc for size 2 French catheter or smaller. Blood must be trasferred to the  Lt Blue/Citrate tube by use of a  blood transfer device to ensure proper fill. 

Specimen should be processed within one hour of collection.

Processing Instructions

Deliver blood to Core Coag bench. Coag Technologist will process.

 

Reject due to: Clotted, hemolyzed, insufficient quantity, or improper collection.

Spin: Y

Aliquot: Y

Temp: -70 C

Storage Location: CPA 2 Freezer ( -70 C) Send Out rack.

 

Specimen should be centrifuged within one hour of collection. Transfer upper 3/4 layer of plasma to plastic tube affixed with large Epic aliquot label. Freeze one aliquot of plasma at -70 C. Preferred plasma volume: 1.0 mL, minimum plasma volume: 0.6 mL. Do not pool. 

 

Off-site collection: Preferred method of collection is venipuncture with vacuum fill. Test results are affected by incorrect blood volumel. Use of a Vascular Access Device for the collection of coag testing is not recommended. If this method is used it requires a 5 cc clearing volume; 3 cc for size 2 French catheter or smaller. Blood must be trasferred to the Lt Blue/Citrate tube by use of the blood transfer device. 

Specimen should be centrifuged within one hour of collection. Transfer upper 3/4 layer of plasma to plastic tube affixed with large Epic aliquot label. Freeze one aliquot of plasma at -70 C. Preferred plasma volume: 1.0 mL, minimum plasma volume: 0.6 mL. Do not pool. 

Stability

Specimen Type Temperature Time
  Room temp N
  Refrigerated N
  Frozen Y

 

Availability

STAT Performed TAT
Yes, M - F 8 am - 3 pm. Drawn daily, Performed M - F at HMC Coag Lab 1 - 3 d

 

Performing Laboratory

University of Washington

Dept. of Laboratory Medicine

Harborview Medical Center Coag Lab

1959 NE Pacific St, NW220
Seattle, WA 98195

 

Phone Number: (206) 520-4600

Department

Department:  Send Outs

 

Phone Number: (206) 987-2563

 

CPT Codes

85270

 

Methodology

Method: Stago STA Clottable Factor assay

Analytical Volume: 1.0 mL citrate plasma

Limitations:

Reference Range

0 - 1 month 23 - 150%
1 - 3 months 27 - 150%
3 - 6 months 41 - 150%
6m - 1 year 38 - 150%
> 1 year 50 - 150%

 

Send Out Instructions

Reference Test Name: Factor XI (11) Activity Assay
Reference Test Number: F11
Instructions: Send routines M - F with the UW courier.