Home
HelpTest Code Fluoxetine Fluoxetine, Serum
Reporting Name
Fluoxetine, SUseful For
Monitoring serum concentration of fluoxetine during therapy
Evaluating potential toxicity
Evaluating patient compliance
Specimen Required
Collection Container/Tube: Red top (serum gel/SST are not acceptable)
Submission Container/Tube: Plastic vial
Specimen Volume: 1 mL
Collection Instructions:
1. Draw blood immediately before the next scheduled dose (trough).
2. Centrifuge and aliquot serum into plastic vial within 2 hours of collection.
Specimen Type
Serum RedSpecimen Minimum Volume
0.5 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Serum Red | Refrigerated (preferred) | 28 days | |
| Frozen | 28 days | ||
| Ambient | 72 hours |
Day(s) Performed
Wednesday
TAT: 3 - 10 days
Performing Laboratory
Mayo Clinic Laboratories in Rochester
Method Name
Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)
Method Description
Serum samples containing fluoxetine and norfluoxetine are diluted in an aqueous solution containing deuterated internal standards and then injected onto a high-turbulence liquid chromatography system for online extraction. Detection is by tandem mass spectrometry.(Unpublished Mayo method)
Reference Values
Fluoxetine + Norfluoxetine: 120-500 ng/mL
Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.CPT Code Information
80299
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| FLUOX | Fluoxetine, S | 78437-1 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 80228 | Fluoxetine, S | 74982-0 |
| 251 | Norfluoxetine, S | 3868-7 |
| 252 | Fluoxetine+Norfluoxetine | 74948-1 |
Report Available
1 to 8 daysReject Due To
| Gross hemolysis | OK |
| Gross lipemia | OK |
| Gross icterus | OK |
Forms
If not ordering electronically, complete, print, and send a Therapeutics Test Request (T831) with the specimen.