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HelpTest Code LAB112 Alkaline Phosphatase, Serum
Clinical System Name
Alkaline Phosphatase, Serum
Description
Alkaline phosphatase is present mainly in kidney, bone, liver, intestine, placenta, and lung. Serum alkaline phosphatase may be elevated in increased bone metabolism; hyperparathyroidism; Paget's disease of bone; carcinoma metastatic to bone; osteogenic sarcoma; and Hodgkin's disease if bones are invaded. Hepatobiliary diseases involving cholestasis, inflammation, and cirrhosis increase alkaline phosphatase activity, as does renal infarction.
Sample Requirements
Specimen: Whole Blood
Container(s): Lt. Green/Mint Top Lithium Heparin, Lt. Green/Lithium Heparin Microtainer, Gold SST, Gold Microtainer, Dark Green/Sodium Heparin, Red
Preferred Vol: 1.0 mL
Minimum Vol: 0.5 mL
Note: Test is affected by hemolysis, prolonged exposure to RBC's, EDTA, oxalate, fluoride & prolonged storage at room temperature. Hemolysis & prolonged room temp storage may result in elevated results.
Processing Instructions
Reject due to: Marked hemolysis, age of specimen
Spin: Y
Aliquot: Y
Storage location: CORE 5 Refrigerator
Off-site collection: Specimen should be centrifuged within 2 hours of collection. Spin blood, and transfer serum or plasma to plastic tube and refrigerate.
Stability
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum or Plasma | RT |
≤ 4 d |
| Serum or Plasma | 2-4 C |
≤ 4 d |
| Serum or Plasma | -20 C or -70 C |
≤ 4 d |
Performing Laboratory
Seattle Children's Laboratory
Department
Department: Core Lab Chemistry
Phone Number: 206-987-2617 (Client Services)
Synonyms
LAB112
ALK P
Alk Phos
Phosphatase, Alkaline
Availability
| STAT | Performed | TAT |
|---|---|---|
| Y | 24/7 | 1 h |
Methodology
Method: Spectrophotometric, Enzyme Rate by Vitros 4600
Analytical Volume: 0.02 mL + 0.03 mL dead space.
Reference Range
| Age | Male (IU/L at 37° C) | Female (IU/L at 37° C) |
| 0 - 15 d | 91 - 256 | 91 - 256 |
| 15 d - 1 y | 131 - 476 | 131 - 476 |
| 1 - 10 y | 151 - 342 | 151 - 342 |
| 10 - 13 y | 137 - 425 | 137 - 425 |
| 13 - 15 y | 124 - 474 | 66 - 262 |
| 15 - 17 y | 91 - 339 | 59 - 173 |
| 17 - 19 y | 64 - 158 | 64 - 158 |
| >19 y | 50 - 136 | 50 - 136 |
CPT Codes
84075