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HelpTest Code LAB1971 Urine Bile Acid Profile
Clinical System Name
Urine Bile Acid Profile
Synonyms
Bile acids
Urine Bile Acids
Serum Bile Acids
Sample Requirements
Specimen: Urine
Container(s): Sterile Screw-Capped Container
Preferred Vol: 5.0 - 25.0 mL
Minimum Vol: 1.0 mL
Specimen: Whole Blood
Container(s): Gold/SST or Red
Preferred Vol: 3.0 mL
Minimum Vol: 1.0 mL
Notes: Paired samples preferred. If only urine is available, we will still send it out.
Processing Instructions
Reject due to: Do not collect in or on diapers or cotton balls (Urine). Grossly hemolyzed (Serum).
Spin: N (Urine), Y (Serum)
Aliquot: Y
Temp: -20 C
Storage Location: Transfer urine to a plastic Nalgene bottle affixed with a large Epic label. Do not add any preservatives. Spin blood, place serum in a plastic aliquot tube affixed with a large Epic label. Immediately freeze both samples in the -20 CPA freezer Send Outs rack.
Off-site Collection: Ship frozen samples to Seattle Children's Main Lab.
Stability
| Specimen Type | Temperature | Time |
|---|---|---|
| Room temp | 2 h | |
| Refrigerated | ||
| Urine and Serum | Frozen | 10 y |
Availability
| STAT | Performed | TAT |
|---|---|---|
| N | Alternate F (Urine) and T, F (Serum) | 7 d |
Performing Laboratory
Cincinnati Children’s Hospital
Mass Spectrometry Lab - MLC 7019
3333 Burnet Avenue
Cincinnati, OH 45229-3099
Phone: (513) 636-4203
Department
Department: Send Outs
Phone: (206) 987-2563
Methodology
Method: Fast Atom Bombardment - Mass Spectrometry (FAB-MS)
Analytical Volume: 1.0 mL Urine
Limitations: Results may be difficult to interpret if ursodeoxycholic acid (UDCA) has been administered. Specimens should be collected prior to administration of UDCA, or after 5 days off UDCA.
Reference Range
Interpretive report is provided.
Send Out Instructions
| Reference Test Name: |
Bile Acids, Urine Bile Acids, Serum |
| Reference Lab Test Code: | |
| Instructions: | Send out on dry ice Monday through Thursday via FedEx Priority Overnight delivery. |
Description
This test is used to screen for inborn errors in bile acid synthesis and metabolism. Results may be difficult to interpret if ursodeoxycholic acid (UDCA) has been administered. Specimens should be collected prior to administration of UDCA, or after 5 days off UDCA.