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GENERAL INFORMATION

 

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Mayo Clinic Laboratories

Test Code LAB2 Copper, Liver Tissue

Additional Codes

Copper L

Reporting Name

Copper, Liver Ts
Seattle Children's Hospital Note:

SCH Clinical System Name: Copper, Liver Tissue

Useful For

Diagnosing Wilson disease and primary biliary cirrhosis using liver tissue specimens


Specimen Required


Supplies: Metal Free Specimen Vial (T173)

Container/Tube:

Preferred: Mayo metal-free specimen vial

Acceptable: Paraffin block, with no more than 1 or 2 cuts previously made

Specimen Volume: 2 mg

Collection Instructions: Two mg of liver tissue is required. This is typically a piece of tissue from a 22-gauge needle biopsy at least 2 cm long. If an 18-gauge needle is used, the tissue must be at least 1 cm in length.

Specimen Stability Information:

Fresh or formalin-fixed liver tissue specimens: Frozen (-30 to -10° C) at least 20 years

Paraffin-embedded (block) liver tissue specimens: Ambient (16 to 24° C) at least 12 1/2 years

Additional Information: Paraffin blocks will be returned 7 days after analysis is complete.


Specimen Type

Liver Tissue

Specimen Minimum Volume

Needle biopsy: See Specimen Required; 2 mm x 2 mm (punch): 0.3 mg by dry weight

Specimen Stability Information

Specimen Type Temperature Time
Liver Tissue Refrigerated (preferred)
  Ambient 
  Frozen 

Day(s) Performed

Monday, Thursday

Seattle Children's Hospital Note:

TAT: 4 - 7 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Method Name

Inductively Coupled Plasma Mass Spectrometry (ICP-MS)

Method Description

The metal of interest is analyzed by inductively coupled plasma mass spectrometry.(Unpublished Mayo method)

Reference Values

<50 mcg/g dry weight

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information

82525

LOINC Code Information

Test ID Test Order Name Order LOINC Value
CUT Copper, Liver Ts 8198-4

 

Result ID Test Result Name Result LOINC Value
8687 Copper, Liver Ts 8198-4

Report Available

3 to 6 days

Reject Due To

  All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.

Forms

If not ordering electronically, complete, print, and send a Gastroenterology and Hepatology Test Request (T728) with the specimen.

Seattle Children's Hospital Additional Information:

Aliases: Copper (Cu); Cu (Copper); Metals, Tissue; Wilson's Disease