Test Code LAB2356 Copper, 24 Hour, Urine
Additional Codes
COPPER U
Reporting Name
Copper, 24 Hr, USCH Clinical System Name: Urine Copper Quantitation
Useful For
Investigation of Wilson disease and obstructive liver disease using a 24-hour urine specimen
Necessary Information
24-Hour volume (in milliliters) is required.
Specimen Required
Patient Preparation: High concentrations of barium are known to interfere with this test. If barium-containing contrast media has been administered, the specimen should not be collected for at least 96 hours.
Supplies: Urine Tubes, 10 mL (T068)
Collection Container/Tube: Clean, plastic urine collection container with no metal cap or glued insert
Submission Container/Tube: Plastic urine tube or clean, plastic aliquot container with no metal cap or glued insert
Specimen Volume: 10 mL
Collection Instructions:
1. Collect urine for 24 hours.
2. Refrigerate specimen within 4 hours of completion of 24-hour collection.
3. See Metals Analysis Specimen Collection and Transport for complete instructions.
Additional Information: See Urine Preservatives-Collection and Transportation for 24-Hour Urine Specimens for multiple collections.
Specimen Type
UrineSpecimen Minimum Volume
0.4 mL
Specimen Stability Information
Specimen Type | Temperature | Time |
---|---|---|
Urine | Refrigerated (preferred) | 28 days |
Ambient | 28 days | |
Frozen | 28 days |
Day(s) Performed
Monday, Thursday
TAT: 3 - 8 days
Performing Laboratory

Method Name
Triple-Quadrupole Inductively-Coupled Plasma-Mass Spectrometry (ICP-MS/MS)
Method Description
The metal of interest is analyzed by triple-quadrupole inductively-coupled plasma mass spectrometry.(Unpublished Mayo method)
Reference Values
0-17 years: Not established
≥18 years: 9-71 mcg/24 h
Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.CPT Code Information
82525
LOINC Code Information
Test ID | Test Order Name | Order LOINC Value |
---|---|---|
CUU | Copper, 24 Hr, U | 5633-3 |
Result ID | Test Result Name | Result LOINC Value |
---|---|---|
8590 | Copper, 24 Hr, U | 5633-3 |
TM7 | Collection Duration | 13362-9 |
VL4 | Urine Volume | 3167-4 |
Special Instructions
Report Available
2 to 5 daysReject Due To
All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.Forms
If not ordering electronically, complete, print, and send 1 of the following forms with the specimen:
Aliases: Copper (Cu), Wilson's Disease, Wilson Disease