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Test Code LAB2370 5-Methyltetrahydrofolate, CSF

Important Note

Specimens collected for this test may also be used for CSF Neurotransmitter Metabolites, CSF Neopterin, and/or CSF Tetrahydrobiopterin/Neopterin profile - all performed at the same reference laboratory. Separate CSF specimens should be submitted for all other testing.

CPA: The MNG CSF Collection Tubes can be found in the yellow bucket on the top shelf of the CPA refrigerator.

Additional Codes

5-MTHF CSF

Clinical System Name

5-Methyltetrahydrofolate, CSF

Synonyms

5 MTHF CSF

Sample Requirements

Specimen: Cerebrospinal Fluid

Container(s): See Comments

Preferred Vol: 4.5 mL

Minimum Vol: 1.5 mL split between tubes #1 - #3 (0.5 mL each; run the risk of not being able to add other testing)

 

Note: Call the Main Lab for appropriate specimen collection containers. Each set consists of five numbered micro-centrifuge tubes. One complete set of tubes is required per patient. Fill each tube to the marked line. Place the tubes on ice at the bedside immediately after collection. Hand deliver specimens to the Main Lab immediately.

 

Processing Instructions

Reject due to:

Spin: N

Aliquot: N

Temp: -70 C

Storage Location: LAB ASSISTANTS: give specimens to the Send Outs department immediately. IF SEND OUTS NOT AVAILABLE: If the sample is blood contaminated, the tubes should immediately be centrifuged and the clear CSF transferred to new similarly labeled tubes. Freeze all five specimen tubes together in the -70 freezer Send Outs rack ASAP following collection.

 

Off-site Collection: No off-site collection.

Stability

Specimen Type Temperature Time
CSF Room temp Unacceptable
  Refrigerated Unacceptable
  Frozen Y

 

Availability

STAT Performed TAT
N    10 - 14 d

 

Performing Laboratory

Medical Neurogenetics (MNG) Laboratories

5424 Glenridge Drive NE

Atlanta, GA 30342

 

Phone: (678) 225-0222

Department

Department: Send Outs

Phone: (206) 987-2563

CPT Codes

82542

Methodology

Method: HPLC/Electrochemistry

Analytical Volume: 0.5 mL CSF

Limitations:

Reference Range

AGE (Years) 5-MTHF nmol/L
0 - 0.2 40-240
0.2 - 0.5 40-240
0.5 - 2.0 40-187
2.0 - 5.0 40-150
5.0 - 10 40-128
10 - 15 40-120
Adults 40-120

 

Send Out Instructions

Reference Test Name: 5-Methyltetrahydrofolate (CSF)
Reference Lab Test Code: NC01
Instructions:

If the sample is blood contaminated, the tubes should be centrifuged immediately and the clear CSF should be transferred to new, similarly labeled tubes. Freeze all five specimen tubes together in the -70 freezer Send Outs rack ASAP after collection. Ship on dry ice. Saturday deliveries are accepted.