Home
HelpTest Code LAB2798 Anti Neutrophil Antibody by Flow Cytometry >4 months old
Clinical System Name
Anti Neutrophil Ab by Flow >4 months old
Synonyms
Granulocyte Antibody Screen >4 months old
Granulocyte Ab Screen >4 months old
Anti Neutrophil Antibodies - Auto
Neutrophil Autoantibodies
Neutrophil Antibodies - Auto
Anti Neutrophil AB by Flow >4 months old
Granulocyte Antibody Screen
Sample Requirements
Specimen: Whole Blood
Container(s): Gold SST; Red also acceptable
Preferred Vol: 2 mL
Minimum Vol: 2 Gold Microtainers
Note: Parents' blood not required for this assay. Draws may be done at any time.
Processing Instructions
Reject due to: n/a - send to lab
Spin: Y
Aliquot: Y
Temp: 2-8 degrees, Refrigerator
Storage location: Refrigerate in plastic aliquot container and include labels and a copy of requisition. Store in 2-8 Refrigerator, Send Outs rack.
Off-site collection: Spin sample, refrigerate serum in plastic aliquot container.
Stability
| Temperature | Time |
|---|---|
| Room temp | 4 hours |
| Refrigerated | 1 week |
| Frozen |
yes, acceptable but not preferred. |
Availability
| STAT | Performed | TAT |
|---|---|---|
| N | Processed daily; testing performed in batches | < 2 weeks |
Performing Laboratory
Versiti Wisconsin
Platelet and Neutrophil Immunology Laboratory
638 North 18th Street
Milwaukee, WI 53233-2121
Phone Number: (800) 245-3117 x6250
Department
Department: Send Outs
Phone Number: (206) 987-2563
CPT Codes
86021
Methodology
Method: Flow Cytometry
Analytical Volume: 500 microL serum
Limitations:
Reference Range
| Negative |
Send Out Instructions
| Reference Test Name: | Neutrophil Antibody Screen |
| Reference Test Number: | 5102 |
| Instructions: | Send refrigerated sample(s) on ice pack(s) via FedEx Priority overnight shipping. Saturday deliveries are acceptable. |
Description
Antineutrophil antibody >4 months testing is used to identify the presence of anti-neutrophil antibodies in patients with suspected autoimmune neutropenia.
Clinical Utility
Autoimmune neutropenia is seen when a person's immune system produces autoantibodies directed against the neutrophilic proteins on neutrophils.
The anti-neutrophil autoantibodies destroy neutrophils leading to neutropenia and subsequent increased risk for infection.
Autoimmune neutropenia typically spontaneously resolves within 2 years.
Identification of anti-neutrophil autoantibodies can help to exclude other inherited forms of neutropenia.