Test Code LAB2937 CoEnzyme Q10 Level, Leukocytes
Additional Codes
WBC CoQ10
Clinical System Name
CoEnzyme Q10 Level, Leukocytes
Synonyms
Leukocyte, Intracellular Coenzyme Q10; Ubiquinone
Sample Requirements
Specimen: Whole Blood
Container(s): Yellow/ACD A or B
Preferred Vol: 5.0 mL
Minimum Vol: 2.0 mL
Notes: An ACD tube can be obtained from the Main Lab. The collection tube can be either ACD solution A or ACD solution B; both are acceptable.
Processing Instructions
Reject due to: Hemolyzed sample; Incorrect collection tube (Gold SST); Received frozen
Spin: N
Aliquot: N
Temp: 2 - 8 C
Storage Location: Affix a large Epic label to the sample(s) and place in CPA1 refrigerator Send Outs rack.
Off-site Collection: Send whole blood refrigerated.
Stability
Specimen Type | Temperature | Time |
---|---|---|
Whole Blood | Room Temp | 5 d |
Refrigerated | 5 d | |
Frozen | Unacceptable |
Availability
STAT | Performed | TAT |
---|---|---|
N | 10 - 14 d |
Performing Laboratory
Medical Neurogenetics (MNG) Laboratories
5424 Glenridge Drive NE
Atlanta, GA 30342
Phone: (678) 225-0222
Department
Department: Send Outs
Phone: (206) 987-2563
CPT Codes
82542
Methodology
Method: HPLC/Electrochemistry
Analytical Volume: 2.0 mL Whole Blood
Limitations:
Reference Range
Interpretive report is provided.
Send Out Instructions
Reference Test Name: | Coenzyme Q10 (Leukocytes) |
Reference Lab Test Code: | MET04 |
Instructions: | Ship on an ice pack via FedEx Priority Overnight. Saturday deliveries are accepted. |
Description
Coenzyme Q10 is produced by the body and is necessary for basic cell functioning. Deficiencies in coenzyme Q10 can be primary or secondary. Primary coenzyme Q10 deficiency is a rare autosomal recessive genetic condition with clinically heterogeneous presentation that can include:
- encephalopathy
- seizures
- ataxia
- cardiomyopathy
- renal failure
- cerebellar atrophy
- Leigh Syndrome
- growth retardation
- delayed motor development
- lactic acidemia
- hypergonadotropic hypogonadism/myopathy
These individuals will have decreased levels of coenzyme Q10 in plasma as well as in skeletal muscle. Secondary coenzyme Q10 deficiency has been seen in individuals with several chronic disorders such as heart conditions, muscular dystrophies, and mitochondrial disorders (such as MELAS and Kearns-Sayre). Additionally, some prescription drugs can lead to a decrease in coenzyme Q10 levels.