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HelpTest Code LAB3397 Posaconazole Level
Clinical System Name
Posaconazole Level
Synonyms
Antifungal drug
Noxafil
Pos
Sample Requirements
Specimen: Whole blood
Container(s): Red
Preferred Vol:1 mL
Minimum Vol: 1 mL
Note: Please allow a minimum of 72 h after starting or changing a dose before drawing a Posaconazole level. Draw trough level 30-60 min before next dose. Microtainers and gel separators are unacceptable.
CSF is also not an acceptable specimen. If CSF is indicated, please order a miscellaneous test communication to send to Fungal Laboratory at UT.
Processing Instructions
Reject due to: Serum separator tubes
Spin: Y
Aliquot:Y
Temp: - 20 C
Storage location: Freeze 0.4 mL serum/plasma in CPA Freezer, Fz5 rack.
Off-site collection: Transfer 0.4 mL serum/plasma in plastic tube and store and send frozen.
Stability
| Specimen Type | Temperature | Time |
|---|---|---|
| serum | Room temp | 1 d |
| Refrigerated | 1 w | |
| Frozen | 6 m |
Availability
| STAT | Performed | TAT |
|---|---|---|
| N | M-F | M-F: Same day if received by 10:00; 1-3 d |
Performing Laboratory
Seattle Children's Laboratory
Department
Department: Chemistry
Location: Chem West
Phone Number: (206) 987-2617
CPT Codes
80299
Methodology
Method: LC/MS/MS
Analytical Volume: 0.25 mL serum
Limitations:
Reference Range
Trough therapuetic range >/= 700 ng/mL
Posaconazole levels of >500 ng/mL have been shown to be effective for prophylaxis management.