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Test Code LAB3459 Soluble Interleukin-2R Level

Important Note

This testing changed from a send-out test to ARUP to a Seattle Children's Hospital test on December 12, 2025. 

Additional Codes

IL2R

Clinical System Name

Soluble Interleukin-2R Level

Synonyms

CD25; cytokine; cytokines; IL 2 Receptor; IL-2R; IL2R; Interleukin 2 Receptor

Sample Requirements

Specimen: Whole Blood

Container(s): Lavender/EDTA

Preferred Vol: 2.0 mL

Minimum Vol: 1.0 mL

Notes: Plasma must be separated from cells within TWO hours of collection (CRITICAL FROZEN).

Processing Instructions

Reject due to: Whole blood sent frozen or refrigerated.

Spin: Y

Aliquot: Y

Plasma: -20 C (CRITICAL FROZEN)

Storage Location: CPA freezer Fz5

 

Off-site Collection: Spin down and freeze plasma. Transport frozen.

Stability

Specimen Type Temperature Time
EDTA plasma Room temp 30 m
  Refrigerated 2 d
  Frozen 6 mo

 

Availability

STAT Performed TAT
N Twice weekly 2-7 d

 

Performing Laboratory

Seattle Children's Hospital

Department

Department: Chemistry

Phone: 206-987-2565

Methodology

Method: Siemens Immulite

Analytical Volume: 0.4 mL Plasma

Limitations: 

Heterophilic antibodies in human serum can react with the immunoglobulins included in the assay components causing interference with in vitro immunoassays. Samples from patients routinely exposed to animals or animal serum products can demonstrate this type of interference potentially causing an anomalous result. These reagents have been formulated to minimize the risk of interference; however, potential interactions between rare sera and test components can occur.

The drug asfotase alfa (STRENSIQ), a recombinant form of alkaline phosphatase, is expected to interere with this assay as this assay utilizes an alkaline phospatase detection system.

Reference Range

<3 years 398-1940 U/mL
3-8 years  144-1329 U/mL
≥8 years 137-838 U/mL

CPT Codes

83520

Description

Primarily used for research and to support attempts to understand the pathogenesis of immune, infectious, allergic, or inflammatory disorders.