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HelpTest Code LAB3538 Arterial Aneurysm Panel
Clinical System Name
Arterial Aneurysm Panel
Synonyms
Core Familial Aneurysm Panel
VscAnP
Vascular Aneurysm Genomic Panel
Arterial Aneurysm Panel
Aortic Aneurysm Panel
Description
Panel sequencing to analyze genetic causes of familial arterial aneurysms, including Marfan Syndrome, Loeys-Dietz Syndrome, Vascular Ehlers-Danlos Syndrome, and Thoracic Aortic Aneurysm and Dissection (TAAD).
Sample Requirements
Specimen: Whole Blood
Container(s): Lavender/EDTA
Preferred Vol: 5.0 mL (adults)
Minimum Vol: 3.0 mL, 2 mL (infants)
Specimen: DNA
Container(s): Sterile Plastic Tube
Preferred Vol: 5 µg DNA at a minimum concentration of ≥ 200 ng/µL
Alternate Specimens (saliva/buccal): See the Alternate Specimen Collection Kits for Genetic Testing page
Processing Instructions
Reject due to:
Spin: N
Aliquot: N
Temp: RT
Storage location: Do not spin. Whole blood may be stored at 4°C until shipped and is stable for 3 - 5 days in the refrigerator.
Off-site collection: Do not spin. Keep whole blood at room temperature.
Stability
| Specimen Type | Temperature | Time |
|---|---|---|
| Whole Blood | Room temp |
3 d |
| Whole Blood | Refrigerated | 7 d |
| Whole Blood | Frozen |
N |
| Extracted DNA | Room temp | 3-4 d |
| Extracted DNA | Refrigerated | 1 y |
| Extracted DNA | Frozen | Indefinitely |
Availability
| STAT | Performed | TAT |
|---|---|---|
| N | Drawn daily | 5 - 7 w |
Performing Laboratory
University of Washington Collagen Diagnostic Laboratory
Department of Laboratory Medicine
Lab H-561 Health Sciences
1959 NE Pacific St, NW220
Seattle, WA 98195
Phone Number: (206) 520-4600
Genetic Counselors: (206) 543-5464
Department
Department: Send Outs/Genetic
Phone Number: (206) 987-2563
Methodology
Next-generation sequencing of exons for select genes
Clinical Utility
A genetic diagnosis may have implications for treatment, management, recurrence risk, and family member testing.
Send Out Instructions
| Reference Test Name: | Arterial Aneurysm Panel |
| Reference Test Number: |
None specified |
| Instructions: |
Use a UW Collagen Diagnostic Laboratory Requisition (see above).
Send to: Peter Byers, MD Collagen Diagnostic Laboratory Lab H-561 Health Sciences Bldg.
Or send refrigerated sample with the UW courier Monday - Friday. |