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HelpTest Code LAB3552 Voriconazole Level
Clinical System Name
Voriconazole Level
Synonyms
Antifungal drug
Vor
VORICONZ
Sample Requirements
Specimen: Whole blood
Container(s): Red
Preferred Vol:1 mL
Minimum Vol: 1 mL
Note: Please allow a minimum of 72 h after starting or changing a dose before drawing a Voriconazole level. Draw trough level 30-60 min before next dose. Microtainers are unacceptable.
Processing Instructions
Reject due to: Serum separator tubes
Spin: Y
Aliquot:Y
Temp: - 20 C
Storage location: Freeze 0.4 mL serum in CPA Freezer, Fz5 rack.
Off-site collection: Transfer 0.4 mL serum in plastic tube and store and send frozen.
Stability
| Specimen Type | Temperature | Time |
|---|---|---|
| Room temp | 1 d | |
| Refrigerated | 1 w | |
| Frozen | 6 m |
Availability
| STAT | Performed | TAT |
|---|---|---|
| N | M-F | Same day if received by 10:00; 1-3 d |
Performing Laboratory
Seattle Children's Laboratory
Department
Department: Chemistry
Location: Chem West
Phone Number: (206) 987-2617
CPT Codes
80299
Methodology
Method: LC/MS/MS
Analytical Volume: 0.15 mL serum
Limitations:
Reference Range
Trough therapeutic range 1 - 5.5 mcg/mL
Trough level (ie, immediately before next dose) monitoring is recommended. Trough levels >6 mcg/mL (and especially >10 mcg/mL) have been associated with toxicity in several reports. Trough levels <1 mcg/mL have been associated with suboptimal response in several reports.
Critical Values
> 10.0 mcg/mL