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HelpTest Code LAB3586 Glycine CSF & Plasma
Clinical System Name
Glycine CSF and Plasma
Synonyms
Gly CSF Pla
Sample Requirements
Specimen: Cerebral Spinal Fluid and Whole Blood
Container(s): Sterile Screw-Capped Container/ Tube/Syringe; Dark Green/Sodium Heparin, Lt. Green/Lithium Heparin
Preferred Vol: 0.5 mL/ 1 mL
Minimum Vol: 0.25 mL/ 0.5 mL
Processing Instructions
Reject due to:
Spin:Y
Aliquot:Y
Temp:-20 C
Storage location: -20 C BCG Box
Off-site collection: Spin, freeze and ship frozen.
Stability
| Temperature | Time |
|---|---|
| Room temp | ≤ 2 hr |
| Refrigerated | < 24 hrs |
| Frozen | 1 month |
Availability
| STAT | Performed | TAT |
|---|---|---|
| N | M-F | 3 days |
Contact the Biochemical Genetics Lab for requests outside of stated availability (206)987-2216.
Performing Laboratory
Seattle Children's Laboratory
Department
Department: Biochemical Genetics
Phone Number: 206-987-2216
CPT Codes
82131
Methodology
Method: Ion exchange chromatography with post column derivatization
Analytical Volume: 0.1 mL
Limitations:
Description
Paired CSF and plasma glycine for diagnosis of non-ketotic hyperglycinemia
Requisition
Biochemical Genetics Requisition
On the requisition include clinical information needed for appropriate interpretation. (Age, gender, diet (e.g. TPN therapy), drug therapy and family history)
Clinical Utility
Diagnosis of non-ketotic hyperglycinemia
Reference Ranges
| Normal CSF/plasma glycine < 0.08 |
| Classic glycine encephalopathy; CSF/plasma glycine > 0.08 |