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HelpTest Code LAB3787 AAV9 Antibody
Clinical System Name
AAV9 Antibody
Synonyms
Anti-drug Antibody
Description
Adeno-associated viruses (AAVs) are commonly used in gene therapy due to the ease of genome manipulation, ease of purification and safety (1). However, many AAV serotypes commonly infect humans resulting in pre-existing immunity which may reduce the efficiency of gene therapy that utilizes these serotypes (1,2,3). The AAV9 ELISA detects antibodies against AAV9 which may inhibit the efficacy of gene therapies (1,2).
Sample Requirements
Specimen: Blood
Container(s): Gold/SST (Red accepted)
Preferred Vol: 4 mL
Minimum Vol: 1 mL
Processing Instructions
Reject due to: Turbidity
Spin: Y
Aliquot: Y
Temp: 2-8° C
Storage location: Store sample at 2-8° C until shipped (Refrigerated)
Off-site collection:
Store and ship refrigerated; send to main campus with courier.
Stability
| Specimen Type | Temperature | Time |
|---|---|---|
| Tissue | Room temp |
72 hours |
| Refrigerated | 14 days | |
| Frozen |
14 days |
Availability
| STAT | Performed | TAT |
|---|---|---|
| N | Collected daily | 3-5 days |
Performing Laboratory
Athena Diagnostics
200 Forest Street, 2nd Floor
Marlborough, MA 01752
Phone Number: (800) 394-4493, Extension 2
Department
Department: Send Outs
Phone Number: (206) 987-2563
Methodology
Method: Enzyme Linked Immunosorbent Assay
Analytical Volume: 0.5mL serum
Limitations:
Reference Range
<1:25
CPT Codes
86790
Send Out Instructions
| Reference Test Name: | AAV9 Antibody Test |
| Reference Test Number: | |
| Instructions: |
Ship via FedEx overnight. Fill out a copy of the Athena requisition found online. Ship Mon - Thu refrigerated. |