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Test Code LAB383 CreatiNINE

Clinical System Name

CreatiNINE

Synonyms

LAB1765

CREAT

Sample Requirements

Specimen: Whole Blood

Container(s): Lt. Green/Mint Top Lithium Heparin, Lt. Green/Lithium Heparin Microtainer, Gold SST, Gold Microtainer, Dark Green/Sodium Heparin, Red

Preferred Vol: 1.0 mL

Minimum Vol: 0.5 mL

Note:  Method is affected by gross hemolysis and lipemia. Not affected by heparin.

Processing Instructions

Reject due to: Hemolysis, Age of specimen

Spin: Y

Aliquot: Y

Storage location: Core 5 Chemistry Refrigerator

 

Off-site collection: Avoid hemolysis. Specimen should be centrifuged within 2 hours of collection. Spin blood and transfer serum or plasma to plastic tube and refrigerate or freeze.

Stability

Specimen Type Temperature Time
Serum or Plasma RT

≤ 5 d

Serum or Plasma 2-8oC

≤ 30 d

Serum or Plasma -20oC or -70oC

≤ 365 d

Availability

STAT Performed TAT
Y 24/7 1 h

Performing Laboratory

Seattle Children's Laboratory    

Department

Department:  Core Chemistry

Phone Number: 206-987-2617 (Client Services)

CPT Codes

82565

Methodology

Method:  Two Point Rate by Vitros 4600

Analytical Volume:  0.02 mL + 0.03 mL dead space

Reference Range

 Age mG/dL
0 - 1 W 0.2 - 1.1
1 W- 2 M ≤ 0.6
2 M- 2 Y ≤ 0.4
2 Y- 10 Y ≤ 0.6
10 Y- 14 Y 0.2 - 0.9
> 14 Y 0.2 - 1.1

Description

Serum creatinine is increased in acute or chronic renal failure, urinary tract obstruction, reduced renal blood flow, shock, dehydration, exercise, and rhabdomyolysis.  Causes of low serum creatinine concentration include debilitation, and decreased muscle mass. The creatinine clearance rate is unreliable if the urine flow is low.  Since urinary creatinine is excreted mainly by glomerular filtration, with only small amounts due to tubular secretion, serum creatinine and a 24-hour urine creatinine excretion can be used to estimate the glomerular filtration rate.