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HelpTest Code LAB383 CreatiNINE
Clinical System Name
CreatiNINE
Description
Serum creatinine is increased in acute or chronic renal failure, urinary tract obstruction, reduced renal blood flow, shock, dehydration, exercise, and rhabdomyolysis. Causes of low serum creatinine concentration include debilitation, and decreased muscle mass. The creatinine clearance rate is unreliable if the urine flow is low. Since urinary creatinine is excreted mainly by glomerular filtration, with only small amounts due to tubular secretion, serum creatinine and a 24-hour urine creatinine excretion can be used to estimate the glomerular filtration rate.
Sample Requirements
Specimen: Whole Blood
Container(s): Lt. Green/Mint Top Lithium Heparin, Lt. Green/Lithium Heparin Microtainer, Gold SST, Gold Microtainer, Dark Green/Sodium Heparin, Red
Preferred Vol: 1.0 mL
Minimum Vol: 0.5 mL
Note: Method is affected by gross hemolysis and lipemia. Not affected by heparin.
Processing Instructions
Reject due to: Hemolysis, Age of specimen
Spin: Y
Aliquot: Y
Storage location: Core 5 Chemistry Refrigerator
Off-site collection: Avoid hemolysis. Specimen should be centrifuged within 2 hours of collection. Spin blood and transfer serum or plasma to plastic tube and refrigerate or freeze.
Stability
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum or Plasma | RT |
≤ 5 d |
| Serum or Plasma | 2-8oC |
≤ 30 d |
| Serum or Plasma | -20oC or -70oC |
≤ 365 d |
Performing Laboratory
Seattle Children's Laboratory
Department
Department: Core Chemistry
Phone Number: 206-987-2617 (Client Services)
Synonyms
LAB1765
CREAT
Availability
| STAT | Performed | TAT |
|---|---|---|
| Y | 24/7 | 1 h |
Methodology
Method: Two Point Rate by Vitros 4600
Analytical Volume: 0.02 mL + 0.03 mL dead space
Reference Range
| Age | mG/dL |
| 0 - 1 W | 0.2 - 1.1 |
| 1 W- 2 M | ≤ 0.6 |
| 2 M- 2 Y | ≤ 0.4 |
| 2 Y- 10 Y | ≤ 0.6 |
| 10 Y- 14 Y | 0.2 - 0.9 |
| > 14 Y | 0.2 - 1.1 |
CPT Codes
82565