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HelpTest Code LAB704 Parathyroid Hormone-Related Peptide, Plasma
Additional Codes
PTH-RP
Reporting Name
PTH-Related PeptideSCH Clinical System Name: PTH-Related Peptide
Useful For
Aiding in the evaluation of individuals with hypercalcemia of unknown origin
Aiding in the evaluation of individuals with suspected humoral hypercalcemia of malignancy
The test should not be used to exclude cancer or screen individuals with tumors for humoral hypercalcemia of malignancy.
Specimen Required
Collection Container/Tube: Ice-cooled, lavender top (EDTA)
Submission Container/Tube: Plastic vial
Specimen Volume: 0.7 mL
Collection Instructions:
1. Centrifuge specimen in a refrigerated centrifuge or in chilled centrifuge cups.
2. Aliquot plasma into plastic vial and freeze.
Specimen Type
Plasma EDTASpecimen Minimum Volume
0.25 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Plasma EDTA | Frozen | 30 days |
Day(s) Performed
Monday through Thursday
TAT: 4 - 7 days
Performing Laboratory
Mayo Clinic Laboratories in Rochester
Method Name
Immunochemiluminometric Assay (ICMA)
Method Description
The parathyroid hormone-related peptide (PTHrP) assay is a plate-based chemiluminescent assay utilizing an anti-PTHrP rabbit-polyclonal antibody for capture and an acridinium ester anti-PTHrP goat-polyclonal antibody for detection. The assay targets 1-86 PTHrP.(Ashrafzadeh-Kian S, Bornhorst J, Algeciras-Schimnich A. Development of a PTHrP chemiluminescent immunoassay to assess humoral hypercalcemia of malignancy. Clin Biochem. 2022;105-106:75-80. doi: 10.1016/j.clinbiochem.2022.04.005)
Reference Values
≤4.2 pmol/L
Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.CPT Code Information
82397
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| PTHRP | PTH-Related Peptide | 15087-0 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 81774 | PTH-Related Peptide | 15087-0 |
Report Available
2 to 5 daysReject Due To
| Gross hemolysis | Reject |
| Gross lipemia | OK |
| Gross icterus | OK |
Forms
If not ordering electronically, complete, print, and send a General Request (T239) with the specimen.
Aliases: Humoral Hypercalcemia of Malignancy Factor; Parathyroid Related Polypeptide; Parathyroid Related Protein; PRP; PTH Related Peptide; PTHRP, Plasma; PTH Related Protein; Parathyroid Hormone Related Peptide