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HelpTest Code LAB727 Glomerular Basement Membrane (GBM) Antibodies
Clinical System Name
Glomerular Basement Membrane (GBM) Antibodies
Synonyms
Anti GBM
Anti-GBM
Anti-Glomerular Basement Membrane
Antiglomerular Basement Membrane Antibody
GBM
Glomerular Basement Membrane Antibody
Sample Requirements
Specimen: Whole Blood
Container(s): Gold SST; Red also acceptable
Preferred Vol: 2 mL
Minimum Vol: 1 mL
Processing Instructions
Reject due to:
Spin:Y
Aliquot: Y
Temp: 2-8 C
Storage location: CPA refrigerator, FrigF rack.
Off-site collection: Spin blood, refrigerate 1 mL serum in a polypropylene aliquot tube.
Stability
| Temperature | Time |
|---|---|
| Room temp |
|
| Refrigerated | 7 d |
| Frozen |
6 m |
Availability
| STAT | Performed | TAT |
|---|---|---|
| N * |
M-F |
1-3 d |
*Available STAT only upon approval of Seattle Children's Hospital Pathologist on call.
Performing Laboratory
Seattle Children's Laboratory
Department
Department: Chemistry
Location: Chem East
Phone Number: (206) 987-2617
CPT Codes
83520
Methodology
Method: Immunoassay on Bioplex 2200
Analytical Volume: 0.4 mL serum
Limitations:
Reference Range
| AI | |
| Negative | <1.0 |
| Positive | >1.0 |
Description
This assay is intended for the detection of IgG class antibodies to Glomerular Basement Membrane (GBM) in human serum. It is to be used as an aid in the diagnosis of various autoimmune vasculitic disorders characterized by elevated levels of selected autoantibodies. Anti GBM antibodies aid in the diagnosis of Goodpasture's Syndrome. The reported result is semi-quantitative.