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HelpTest Code LAB874 Cyclosporine Level
Clinical System Name
Cyclosporine Level
Synonyms
CSA
Neoral
Sandimmune
CYCLO
Sample Requirements
Specimen: Whole Blood
Container(s): Lavender/EDTA, Lavender/EDTA Microtainer
Preferred Vol: 1 mL
Minimum Vol: 0.5 mL
Note: Trough levels are collected within one hour of the next dose. Please arrive to the lab 30 – 60 min before the next dose time to allow for probable wait times.
Specimen must be received in the lab by 10:00 for same day results.
If patient is receiving IV cyclo, the lab sample must be drawn off a separate line or from a peripheral source. Assay can also be performed on dried blood spots, but order must be placed for Cyclosporine Level Blood Spot.
Processing Instructions
Reject due to: Frozen specimen.
Spin: N
Aliquot: N
Temp: Store at room temperature.
Storage location: Store specimen and labels in RT1 box.
Off-site collection: Trough levels are collected within one hour of the next dose. Note draw time on the requisition. If patient is receiving IV cyclo, the lab sample must be drawn off a separate line or from a peripheral source. Do not centrifuge. Send refrigerated if sample will not be received in lab within 24 hours. Assay can also be performed on dried bloodspots, but must order Cyclosporine Level Blood Spot.
Stability
| Temperature | Time |
|---|---|
| Room temp | 2 d |
| Refrigerated | 7 d |
| Frozen | N |
Availability
| STAT | Performed | TAT |
|---|---|---|
| N | Daily |
Daily results report out by 14:00 if received in lab by 10:00
Specimens received between 10:00 and 13:00 |
Performing Laboratory
Seattle Children's Laboratory
Department
Department: Chemistry
Location: Chem West
Phone Number: (206)987-2617
CPT Codes
80158
Methodology
Method: LC/MS/MS
Analytical Volume: 50 mcL
Limitations:
Reference Range
| Therapeutic (Trough Level) | Toxic | |
|---|---|---|
| Renal Transplants | 100 - 200 nG/mL | >600 nG/mL |
| Other Transplants | 200 - 300 nG/mL | >600 nG/mL |