Sign in →

Purkinje Cell Cytoplasmic Antibodies, Type 1

Clinical System Name

Miscellaneous Test


Neuronal Nuclear (Yo) Antibody, Purkinje Cell

Anti Yo

Sample Requirements

Specimen: Whole Blood

Container(s): Gold SST or Gold Microtainer or Red

Preferred Vol: 1.0 mL

Minimum Vol: 0.5 mL


Note: Overnight fasting is preferred. Serum is the preferred specimen but CSF (0.8 mL, refrigerated) is also acceptable.

Processing Instructions

Reject due to:

Spin: Y


Temp: 2 - 4 C

Storage location: Spin sample. Transfer serum into a plastic aliquot container. Refrigerate sample in CPA refrigerator send-outs rack.


Off-site collection: Spin sample and transfer serum into a plastic aliquot tube. Transport room temperature.


Specimen Type Temperature Time
Serum Room temp 7 d
  Refrigerated 14 d
  Frozen 21 d



STAT Performed TAT
N Collected daily  Contact Quest for individual test schedules


Performing Laboratory

Quest Diagnostics - Nichols Institute

33608 Ortega Highway
San Juan Capistrano, CA 92690-6130


Phone Number: (800) 553-5445


Department:  Send Outs


Phone Number: (206) 987-2563


Reference Range

Yo Ab Screen IFA Negative
Yo Ab, Western Blot Negative
Yo Ab Titer < 1:40



Method: Immunofluorescence Assay (IFA)

Analytical Volume: 0.2 mL serum or 0.5 ml CSF


CPT Codes



If Yo Antibody Screen, IFA is positive, Yo Antibody, Western Blot will be performed at an additional charge (CPT code(s): 84181).
If Yo Antibody, Western Blot is positive, Yo Antibody Titer will be performed at an additional charge (CPT code(s): 86256)


Send Out Instructions


Reference Test Name: Yo Antibody Screen with Reflex to Titer and Western Blot
Reference Test Number: 90119 (blood)  90117 (CSF)
Instructions: Send out M - F with the Quest courier.