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HelpPurkinje Cell Cytoplasmic Antibodies, Type 1
Clinical System Name
Miscellaneous Test
Synonyms
Neuronal Nuclear (Yo) Antibody, Purkinje Cell
Anti Yo
PCA-1
Sample Requirements
Specimen: Whole Blood
Container(s): Gold SST or Gold Microtainer or Red
Preferred Vol: 1.0 mL
Minimum Vol: 0.5 mL
Note: Overnight fasting is preferred. Serum is the preferred specimen but CSF (0.8 mL, refrigerated) is also acceptable.
Processing Instructions
Reject due to:
Spin: Y
Aliquot:Y
Temp: 2 - 4 C
Storage location: Spin sample. Transfer serum into a plastic aliquot container. Refrigerate sample in CPA refrigerator send-outs rack.
Off-site collection: Spin sample and transfer serum into a plastic aliquot tube. Transport room temperature.
Stability
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum | Room temp | 7 d |
| Refrigerated | 14 d | |
| Frozen | 21 d |
Availability
| STAT | Performed | TAT |
|---|---|---|
| N | Collected daily | Contact Quest for individual test schedules |
Performing Laboratory
Quest Diagnostics - Nichols Institute
33608 Ortega Highway
San Juan Capistrano, CA 92690-6130
Phone Number: (800) 553-5445
Department
Department: Send Outs
Phone Number: (206) 987-2563
CPT Codes
86255
If Yo Antibody Screen, IFA is positive, Yo Antibody,
Western Blot will be performed at an additional charge (CPT
code(s): 84181).
If Yo Antibody, Western Blot is positive, Yo Antibody Titer
will be performed at an additional charge (CPT code(s): 86256)
Methodology
Method: Immunofluorescence Assay (IFA)
Analytical Volume: 0.2 mL serum or 0.5 ml CSF
Limitations:
Reference Range
| Yo Ab Screen IFA | Negative |
| Yo Ab, Western Blot | Negative |
| Yo Ab Titer | < 1:40 |
Send Out Instructions
| Reference Test Name: | Yo Antibody Screen with Reflex to Titer and Western Blot |
| Reference Test Number: | 90119 (blood) 90117 (CSF) |
| Instructions: | Send out M - F with the Quest courier. |