Sign in →

Test Code Tzanck Smr Tzanck Smear Evaluation

Additional Codes

Smears, Histo/Path

Clinical System Name

Tzanck Smear Evaluation


Giant Cell (Tzank Smear)



To confirm or exclude Varicella-zoster / Herpes simplex virus induced vesicles.  Direct smears of base or roof of vesicle is stained and reviewed by pathologist.

Sample Requirements

Specimen:  Vesicle contents smeared on slide

Container(s):  See Note

Preferred Vol:  n/a

Minimum Vol:  n/a

Note: Slide preparation. Using pencil, label slide with patient name, MRN, and collection date. Gently rupture vesicle with #15 scapel blade and scrape debris from vesicle base and underside of roof (do not use cotton swab); smear debris on labeled slide.  A completed surgical pathology request form including hospital number, name, date of birth, date of procedure, pre-op diagnosis, clinical history, ordering physician, and any other pertinent information must be submitted with the specimen.  Deliver air-dried slide with completed requistion to Laboratory CPA.



Processing Instructions

Reject due to: NA

Spin:  N

Aliquot:  N

Temp: RT

Note:  Deliver slide and copy of requisition to Core Hematology for Wright Stain.  Stained slide will be coverslipped and delivered to Pathology.  Tech will result test in Cerner with "Done" after slides are submitted for pathologist review.  Notify tech immediately. 


Off-site collection:  Send labeled smear from a lesion to Laboratory immediately with completed requisition.


Specimen Type Temperature Time
Body Fluid/Smear from Lesion Room temp 48 hours
  Refrigerated N
  Frozen N



STAT Performed TAT
  M-F 8 a.m. - 5 p.m. 1 day


Performing Laboratory

Seattle Children's Laboratory  


Department:  Histology

Phone Number: (206) 987-2580.




Method:  Microscopic review by pathologist of wright stained smear

Analytical Volume:  n/a

CPT Codes

CPT codes will vary depending on tests performed.  Call Client Services for more information (206) 987-2617.


Surgical pathology requisition required.